NCT03568019Active, not recruiting
PET Avidity in Cachexia-Inducing Lung and Gastrointestinal Tumors
Source: ClinicalTrials.gov · Last updated 21 Apr 2026
Brief summary (registry, in English)
PET has an established role in the initial staging of patients with newly diagnosed lung and gastrointestinal tumors.PET avidity is described with both maximum and mean standardized uptake values.Malignant cells have increased activity on PET, defined as the standardized uptake value (SUV), with increased uptake of FDG in tumor due to elevated levels of GLUT receptors, elevated intracellular levels of hexokinase and increased rates of glycolysis. However, there is a subset of patients with lung and gastrointestinal tumors that are not PET avid.These patients may present with clinically and systemically aggressive disease with a declining performance status and/or weight loss.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 10000 (actual)
- First submitted
- 14 May 2018
- Start date
- 26 Nov 2013
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- University of Texas Southwestern Medical Center
- Diseases
- Lung cancer
- NCT number
- NCT03568019
What you commit to
- Study type: Observational
- Participants enrolled: 10000
- From 26 Nov 2013 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- There will be no absolute exclusion criteria as long as the inclusion criteria have been met.
Who the study is looking for
- Patients with histologically proven lung and gastrointestinal cancers, stages I-IV with PET and/or CT within 6 weeks of diagnosis.
Age in the registry: 18 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UT Southwestern Medical Centre Coordinator of this site? Confirm its status | Dallas | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.