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NCT03568019Active, not recruiting

PET Avidity in Cachexia-Inducing Lung and Gastrointestinal Tumors

Source: ClinicalTrials.gov · Last updated 21 Apr 2026

Brief summary (registry, in English)

PET has an established role in the initial staging of patients with newly diagnosed lung and gastrointestinal tumors.PET avidity is described with both maximum and mean standardized uptake values.Malignant cells have increased activity on PET, defined as the standardized uptake value (SUV), with increased uptake of FDG in tumor due to elevated levels of GLUT receptors, elevated intracellular levels of hexokinase and increased rates of glycolysis. However, there is a subset of patients with lung and gastrointestinal tumors that are not PET avid.These patients may present with clinically and systemically aggressive disease with a declining performance status and/or weight loss.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
10000 (actual)
First submitted
14 May 2018
Start date
26 Nov 2013
Primary completion date
31 Dec 2027
Lead sponsor
University of Texas Southwestern Medical Center
Diseases
Lung cancer
NCT number
NCT03568019

What you commit to

  • Study type: Observational
  • Participants enrolled: 10000
  • From 26 Nov 2013 to the primary completion date, 31 Dec 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • There will be no absolute exclusion criteria as long as the inclusion criteria have been met.

Who the study is looking for

  • Patients with histologically proven lung and gastrointestinal cancers, stages I-IV with PET and/or CT within 6 weeks of diagnosis.

Age in the registry: 18 years to 99 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
UT Southwestern Medical Centre
Coordinator of this site? Confirm its status
DallasUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.