NCT03583866Active, not recruitingEarly phase 1
Adiposity and Endothelin Receptor Function
Source: ClinicalTrials.gov · Last updated 6 Feb 2025
Brief summary (registry, in English)
Elevated levels of ET-1 have been implicated in cardiovascular disease and some forms of hypertension. Due to the strong, positive correlation between obesity and hypertension, the present study will explore the contribution of adiposity in ETB receptor function and aim to elucidate if ETB receptor dysfunction is a major contributor to hypertension in obesity.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Early phase 1
- Study type
- Interventional
- Enrollment
- 25 (actual)
- First submitted
- 27 Jun 2018
- Start date
- 21 May 2018
- Primary completion date
- Dec 2025
- Lead sponsor
- Augusta University
- Diseases
- High blood pressure
- NCT number
- NCT03583866
What you commit to
- Study type: Interventional · Early phase 1
- Participants enrolled: 25
- From 21 May 2018 to the primary completion date, Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Using medications that affect vascular tone (i.e., nitrates, etc.)
Other illness
- Evidence of cardiovascular, pulmonary, renal, hepatic, cerebral, or metabolic disease
- If you have uncontrolled hypertension (treated resting SBP \>140 mm Hg or DBP \>90 mm Hg)
Other
- Evidence of pregnancy
- Use of any anticoagulants (i.e. aspirin)
- Anemia
- If you are postmenopausal
Who the study is looking for
- If you are an adult between the ages of 18-40 year old
Age in the registry: 18 years to 40 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Georgia Prevention Institute/ Laboratory of Integrative and Exercise Physiology Coordinator of this site? Confirm its status | Augusta | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.