NCT03594994Completed
Metabolic Effects of Sleep Extension in People With Obesity
Source: ClinicalTrials.gov · Last updated 11 Dec 2025
Brief summary (registry, in English)
This study is designed to determine the impact of extending sleep duration on glucose metabolism in people with obesity. Half of the participants will be instructed to increase their time-in-bed in order to achieve \>7h sleep/night (sleep extension; n=15) while the other half will be be instructed to maintain their current sleep habits (n=15).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 31 (actual)
- First submitted
- 28 Jun 2018
- Start date
- 29 Oct 2018
- Primary completion date
- 15 Jul 2024
- Lead sponsor
- Washington University School of Medicine
- Diseases
- Obesity
- NCT number
- NCT03594994
What you commit to
- Study type: Interventional
- Participants enrolled: 31
- From 29 Oct 2018 to the primary completion date, 15 Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior bariatric surgery
- Tobacco or illicit drug use
Other illness
- Sleep disorders
- moderate to severe sleep apnea (apnea-hypopnea index ≥15 events/hour)
- had ≥15 periodic limb movements per hour sleep \[PLMS\]
- narcolepsy or insomnia
- Significant organ dysfunction/disease (e.g. diabetes mellitus, kidney disease)
- Liver disease other than metabolic dysfunction associated steatotic liver disease (MASLD)
Lab values
- Taking medications that can affect study outcomes (alter sleep duration or glucose metabolism)
Other
- Perform shift work
- Excessive caffeine or alcohol consumption
- Pregnancy or breastfeeding
- Perform intense exercise \>70 min/wk or moderate exercise \>150 min/week
- Excessive alcohol consumption (\>21 units of alcohol per week for men and \>14 units of alcohol per week for women)
Who the study is looking for
- Sleep \<7h/night
- Body mass index 25-50 kg/m2
- Altered glucose metabolism (any of the following) Fasting glucose 100-125 mg/dL or, 2-h plasma glucose 140-199 mg/dL during an oral glucose tolerance test (OGTT) or, HbA1c 5.7-6.4% or, homeostatic model assessment of insulin resistance (HOMA-IR) ≥2.0
Age in the registry: 21 years to 65 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Washington University School of Medicine Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.