NCT03596411Completed
The Detection of Barrett's Esophagus by Gastrointestinal Endoscopy Prevents Esophageal Carcinoma in Morbid Obese After Sleeve Gastrectomy
Refleeve : A Retrospective Study to Evaluate the Prevalence of the Barett's Esophagus by Gastro-osephagal Endoscopy in Morbid Obese Patients Treated by Sleeve Gastrectomy and the Advantage of the Systematic Detection in the Prevention of Esophageal Carcinoma
Source: ClinicalTrials.gov · Last updated 17 Jun 2026
Brief summary (registry, in English)
Severe Gastroesophageal reflux disease (GERD) leading to a chronic aggression of esophagus mucosa, called Barrett's esophagus is a main complication of Sleeve gastrectomy for morbid obesity. Barrett's esophagus is considered as a early stage of neoplastic transformation to adenocarcinoma. Since this last years, six european bariatric centers have adopted the policy to realize endoscopy before and five years or more after sleeve gastrectomy. Investigators worked out a database comprizing the Endoscopic features and patient characteristics. Refleeve projet aim to analyse the long term follow-up datas of 100 patients, evaluate the prevalence of Barret's esophagus and investigate the advantage of the systemetic detection to prevent esophagus adenocarcinomas.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 100 (actual)
- First submitted
- 17 May 2018
- Start date
- 17 May 2018
- Primary completion date
- 17 May 2024
- Lead sponsor
- Centre Hospitalier Universitaire de Nice
- Diseases
- Obesity, Gastric and esophageal cancer
- NCT number
- NCT03596411
What you commit to
- Study type: Observational
- Participants enrolled: 100
- From 17 May 2018 to the primary completion date, 17 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- SG as a conversional procedure from another bariatric procedure such as the gastric banding;
- No upper GI endoscopy before the SG
- Barrett's esophagus before the SG;
- A second procedure after the SG such as the conversion to Roux-en-Y gastric bypass or duodenal switch;
- An upper GI endoscopy done not following the international guidelines for the diagnosis of Barrett's esophagus9.
Who the study is looking for
- Patients who had had SG with a minimum follow-up of 5 years, without signs of Barrett's esophagus before SG;
- An upper GI endoscopy before the SG;
- An upper GI endoscopy indicating that no Barrett's esophagus was present at the time of the SG;
- An upper GI endoscopy done with the scope of searching for the endoscopic anomalies of the Barrett's esophagus according to the international guidelines for the diagnosis of Barrett's esophagus 9.
- Endoscopic biopsies according to the international guidelines for the diagnosis of Barrett's esophagus 9.
Age in the registry: 18 years to 60 years · Sex: All
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Nice Coordinator of this site? Confirm its status | Nice | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.