NCT03611725Completed
Comparison of Success Rate Between Distal Radial Approach and Radial Approach in STEMI
Comparison of Success Rate Between Distal Radial Approach and Radial Approach in ST-segment Elevation Myocardial Infarction
Source: ClinicalTrials.gov · Last updated 22 Aug 2025
Brief summary (registry, in English)
ST-segment elevation myocardial infarction (STEMI) is an emergent disease to treat as soon as possible. 2017 ESC guidelines for the management of STEMI recommend using radial approach (RA) rather than femoral approach (FA) to reduce mortality and bleeding complications if the operators are expert for RA. Recently, Ferdinand Kiemeneij reported that distal radial approach (DRA) could be a feasible and safe route for coronary angiography (CAG) and percutaneous coronary intervention (PCI) in 70 patients. The right-handed patient could feel more comfortable in left DRA than right RA. Left DRA also could provide a better comfortable position for the operator compared to left RA. Distal radial artery is located around the anatomical snuffbox, which doesn't contain nerve and vein beside artery. Therefore, the possibility of procedure-related complications such as nerve injury or arteriovenous fistula is very low. Also, the superficial location of DRA could make easier hemostasis. There were no vascular-related complications from the report of Kiemeneij. But, the rate of puncture failure was 11%, which was higher than RA-based study (5.34% in STEMI patients of RIVAL trial, 6% in RIFLESTEACS trial and 5.8% in MATRIX trial). Nevertheless, this study was a pilot study with a small number of patients. There is no clinical study to compare the feasibility and safety for CAG and PCI between DRA and RA in patients with STEMI. Therefore, this study aimed to evaluate whether DRA is feasible and safe compared to RA in STEMI setting.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 352 (actual)
- First submitted
- 17 Jul 2018
- Start date
- 15 Aug 2018
- Primary completion date
- 7 Mar 2023
- Lead sponsor
- Wonju Severance Christian Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT03611725
What you commit to
- Study type: Interventional
- Participants enrolled: 352
- From 15 Aug 2018 to the primary completion date, 7 Mar 2023
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patient with ipsilateral arteriovenous fistula
Other
- Cardiogenic shock
- Thrombolysis before primary percutaneous coronary intervention
- Inability to obtain written informed consent
- Participation in another ongoing clinical trial
- Pregnancy
- Expected lifespan \<12 months
- \* Eligible operator criteria
- Qualified operator who had experienced ≥ 100 cases of distal radial artery puncture
Who the study is looking for
- Age ≥ 20 years
- ST-segment elevation myocardial infarction
- Palpable unilateral distal radial and radial artery
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kangwon National University College of Medicine Coordinator of this site? Confirm its status | Chuncheon | South Korea | Unknown status |
| The Catholic University of Korea Uijeongbu St. Mary's Hospital Coordinator of this site? Confirm its status | Uijeongbu-si | South Korea | Unknown status |
| Wonju Severance Christian Hospital Coordinator of this site? Confirm its status | Wŏnju | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.