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NCT03611816Recruiting

Biological Bank for Atrial Fibrillation and Stroke

Biological Bank for Studies Related to Atrial Fibrillation and Stroke

Source: ClinicalTrials.gov · Last updated 17 Apr 2026

Brief summary (registry, in English)

Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice. This arrhythmia is responsible for 15% of strokes and more than 30% of strokes on people over 65 years. According to studies, 30 to 40% of isolated atrial fibrillations could be familial. Atrial fibrillation has significant genetic heterogeneity. About 40 genes have been identified as potentially involved. Studies have identified genes common to the risk of atrial fibrillation and stroke. Despite the pathophysiology of atrial fibrillation has been intensively and extensively studied for almost a century, there are still many questions. The pathophysiology is not sufficiently understood to allow finding more effective therapies. It is necessary to identify genetic determinants and thus potentially new pharmacological targets more adapted. The establishment of a biological database will test hypotheses concerning the genetic origin and thromboembolic process of atrial fibrillation and associated stroke.

Status (registry)
Recruiting
Study type
Observational
Enrollment
1000 (estimated)
First submitted
31 Jan 2018
Start date
23 Apr 2018
Primary completion date
23 Apr 2033
Lead sponsor
Hospices Civils de Lyon
NCT number
NCT03611816

What you commit to

  • Study type: Observational
  • Planned participants: 1000
  • From 23 Apr 2018 to the primary completion date, 23 Apr 2033
  • 5 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Criteria the registry did not label

  • Group 1a
  • Inclusion Criteria :
    • \- AF history
  • Exclusion Criteria :
    • No AF history
    • patient who didn't signed consent
    • Group 1b
  • Inclusion Criteria :
    • AF history
    • Scheduled electrophysiological exploration or AF ablation
  • Exclusion Criteria :
    • No AF history
    • pregnant women
    • patient who didn't signed consent
    • Group 1c
  • Inclusion Criteria :
    • AF/AT history
    • Stroke history
  • Exclusion Criteria :
    • No Stroke history
    • patient who didn't signed consent
    • Group 2
  • Inclusion Criteria :
    • patient over 80
    • ECG: sinusal rhythm
    • TTE : no left atrial dilatation
  • Exclusion Criteria :
    • atrial fibrillation history
    • TTE : Left atria \>25cm², \> 34m/m2), FEVG \< 50%
    • ECG : QRS \> 90 ms
    • cardiac pathologies (excepted hypertension and valvulopathies)
    • History of stroke and transient ischemic attack
    • patient who didn't signed consent
    • Group 3
  • Inclusion Criteria :
    • cryptogenic stroke or transient ischemic attack history before 50 yo
    • No AF history
  • Exclusion Criteria :
    • AF history
    • stroke or transient ischemic attack over 50 yo
    • patient who didn't signed consent

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (5)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Service neurologie Centre hospitalier Fleyriat
Coordinator of this site? Confirm its status
Bourg-en-BresseFranceRecruiting
Service d'urgences Neurovasculaires - service de neurologie vasculaire , Hôpital Pierre Wertheimer
Coordinator of this site? Confirm its status
BronFranceRecruiting
Service de rythmologie, hôpital cardiologique Louis Pradel
Coordinator of this site? Confirm its status
BronFranceRecruiting
Service de médecine gériatrique Centre hospitalier Lyon Sud, Groupement hospitalier Sud
Coordinator of this site? Confirm its status
Pierre-BéniteFranceRecruiting
Hôpital des Charpennes
Coordinator of this site? Confirm its status
VilleurbanneFranceRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.