NCT03615794Completed
A Study of Pregnant and Postpartum Women With and Without Mood Disorders
A Prospective Study of Pregnant and Postpartum Women With and Without Mood Disorders
Source: ClinicalTrials.gov · Last updated 30 Dec 2025
Brief summary (registry, in English)
This study is looking at genetic, biological, and environmental causes and how all three may work together to cause postpartum mood episodes. Participants will have psychiatric histories taken and will be monitored throughout pregnancy and during the postpartum period for the development of depressive or other mood episodes. Biological measures, including hormone levels, immunological measures, and growth factors will be collected. Environmental factors such as sleep deprivation and stress will also be measured. These factors will be considered in the setting of genetic and epigenetic data with the hope that investigators will ultimately be able to predict the onset of postpartum mood episodes in this vulnerable population.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 300 (actual)
- First submitted
- 31 Jul 2018
- Start date
- 1 Oct 2017
- Primary completion date
- 31 Jan 2024
- Lead sponsor
- Johns Hopkins University
- Diseases
- Depression, Bipolar disorder
- NCT number
- NCT03615794
What you commit to
- Study type: Observational
- Participants enrolled: 300
- From 1 Oct 2017 to the primary completion date, 31 Jan 2024
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Medical or psychiatric instability
- Presence or development of significant pregnancy conditions that may have independent effects on outcomes
Other
- Current active suicidal ideation
- Active substance abuse or dependence during the last 90 days
Who the study is looking for
- Pregnant women with singleton pregnancies
- With or without a history of a mood disorder (MDD, Bipolar I, Bipolar II or Bipolar NOS)
Age in the registry: 18 years to 50 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| 550 North Broadway Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
| University of Virginia Coordinator of this site? Confirm its status | Charlottesville | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.