NCT03617185Completed
Effect of Exercise and Surgical Weight Loss on Polyneuropathy
The Effect of High Intensity Interval Training and Surgical Weight Loss on Distal Symmetric Polyneuropathy Outcomes
Source: ClinicalTrials.gov · Last updated 17 Sept 2026
Brief summary (registry, in English)
The purpose of this research study is to evaluate how exercise and surgical weight loss affect how likely an individual is to develop peripheral neuropathy and other neurologic complications.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 140 (actual)
- First submitted
- 14 Jul 2018
- Start date
- 27 Jul 2018
- Primary completion date
- 1 Aug 2024
- Lead sponsor
- University of Michigan
- Diseases
- Obesity
- NCT number
- NCT03617185
What you commit to
- Study type: Interventional
- Participants enrolled: 140
- From 27 Jul 2018 to the primary completion date, 1 Aug 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participation in an experimental medication trial within 3 months of starting the study
Other illness
- History of distal symmetric polyneuropathy (DSP) from causes other than diabetes and/or the metabolic syndrome as determined through medical history, family history, history of medications, occupational history, history of exposure to toxins, physical and neurological examinations;
- Undergoing therapy for malignant disease other than basal-cell or squamous-cell skin cancer
- Medical or psychiatric reason for not being a surgical candidate
Other
- Use of warfarin, heparin, or other anticoagulants, which would increase the risk of complications from skin biopsy
- Contraindication to HIIT participation including a failed exercise stress test
- Requiring a walking assist device;
- Currently smoking
Who the study is looking for
- Attending a bariatric surgery clinic
- BMI \> 35 with one comorbid condition present or BMI \> 40 without comorbid conditions present
- Willing and capable to sign the Institutional Review Board (IRB) approved consent form and cooperate with the medical procedures for the study duration
- Willing to accept random treatment assignment to HIIT or routine exercise counseling
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Michigan Coordinator of this site? Confirm its status | Ann Arbor | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.