NCT03634267TerminatedPhase 1
MRI-Guided Brachytherapy in Treating Participants With HPV-Associated Stage IB2-IVA Cervical or Stage II-IVA Vaginal Cancer
MRI Guided Brachytherapy for HPV-Associated Cervical and Vaginal Malignancies
Source: ClinicalTrials.gov · Last updated 15 Sept 2026
Reason given: PI Request
Brief summary (registry, in English)
This trial studies how well magnetic resonance imaging (MRI)-guided internal radiation therapy (brachytherapy) works in treating participants with human papillomavirus (HPV) associated stage IB2-IV cervical or stage II-IVA vaginal cancer. Using MRI guidance during brachytherapy applicator placement may improve treatment planning in participants with cervical or vaginal cancer.
- Status (registry)
- Terminated
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 26 (actual)
- First submitted
- 3 Aug 2018
- Start date
- 3 Aug 2018
- Primary completion date
- 26 Aug 2026
- Lead sponsor
- M.D. Anderson Cancer Center
- Diseases
- Cervical cancer
- NCT number
- NCT03634267
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with implantable cardioverter-defibrillator, pacemaker or other implanted device or medical condition which precludes MRI acquisition.
Other
- Patient or tumor anatomy that requires use of a non-MRI-compatible applicator.
Who the study is looking for
- Women with stage 1B2-IVA cervical cancer recommended to receive definitive chemoradiation including brachytherapy; or
- Women with stage II-IVA vaginal cancer recommended to receive definitive chemoradiation including brachytherapy.
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| M D Anderson Cancer Center | Houston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.