NCT03634397Completed
Predicting Ipsilesional Motor Deficits in Stroke With Dynamic Dominance Model
Source: ClinicalTrials.gov · Last updated 12 Sept 2025
Brief summary (registry, in English)
This study will test the hypothesis that the combination of low-moderate to severe motor deficits in the paretic arm and persistent motor deficits in the less-impaired arm limits functional independence in chronic stroke survivors. We, therefore, predict that intense remediation, focused on improving the speed, coordination, and accuracy of the less-impaired arm should improve functional independence.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 58 (actual)
- First submitted
- 3 Jul 2018
- Start date
- 2 Feb 2019
- Primary completion date
- 22 Feb 2024
- Lead sponsor
- Robert L. Sainburg
- Diseases
- Stroke
- NCT number
- NCT03634397
What you commit to
- Study type: Interventional
- Participants enrolled: 58
- From 2 Feb 2019 to the primary completion date, 22 Feb 2024
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- currently taking prescription drugs with known sedative properties that are interfering with sensory-motor function
Other illness
- a history of:
- neurological disease other than stroke (e.g., head trauma)
- a major psychiatric diagnosis (e.g., schizophrenia, major affective disorder),
- peripheral disorders affecting sensation or movement of the upper extremities, including pain or arthritis
- bilateral stroke
Other
- hospital admission for substance abuse
- significant joint pain that is activity limiting
Who the study is looking for
- neuroradiological confirmation of unilateral brain damage with residual contralesional upper-extremity weakness
- deficits in ipsilesional arm performance assessed by the JTHFT
- 6+ months post stroke
- Demonstrates cognitive abilities
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Penn State College of Medicine Coordinator of this site? Confirm its status | Hershey | United States | Unknown status |
| University of Southern California Coordinator of this site? Confirm its status | Los Angeles | United States | Unknown status |
Related publications
- Targeted Remediation of the Ipsilesional Arm in Chronic Stroke: A Randomized Clinical Trial.JAMA Neurol · 2026 · PMID 41627841
This page is information, not medical advice. Discuss any trial with your doctor.