NCT03649178Completed
Dietary Salt in Rheumatoid Arthritis
Inflammatory and Vascular Response to Dietary Salt in Rheumatoid Arthritis
Source: ClinicalTrials.gov · Last updated 30 Jul 2026
Brief summary (registry, in English)
In this study investigators propose to address the following hypotheses: 1) Reduction in dietary sodium will decrease inflammation in patients with rheumatoid arthritis (RA). 2) Reduction in dietary sodium will decrease blood pressure in patients with RA. 3) Reduction in dietary sodium will decrease tissue sodium in patients with RA.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 18 (actual)
- First submitted
- 23 Aug 2018
- Start date
- 2 Jan 2020
- Primary completion date
- 30 Sept 2024
- Lead sponsor
- Vanderbilt University Medical Center
- Diseases
- Rheumatoid arthritis
- NCT number
- NCT03649178
What you commit to
- Study type: Interventional
- Participants enrolled: 18
- From 2 Jan 2020 to the primary completion date, 30 Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Receiving dialysis
- Organ or bone marrow transplant
- Diabetes mellitus treated with an insulin pump
- Major surgery within the previous 3 months
- Presence of a condition that could make 24-hour blood pressure monitoring difficult: atrial fibrillation, inability to operate machine, receiving anticoagulants, presence of a condition that in the opinion of the investigator may be exacerbated by blood pressure cuff inflation (e.g., lymphedema).
Other illness
- Taking diuretics, uncontrolled hypertension (\>160/100 mmHg), or cardiac failure requiring treatment.
- Severe co-morbid conditions such as active cancer likely to compromise study participation
Other
- Pregnancy
- Severe edema (as judged by the investigator)
- Unwillingness, or other inability, to cooperate
- Contraindication to MRI
Who the study is looking for
- Male and female patients older than 18 years who are willing to participate.
- Satisfy the ACR criteria for the diagnosis of RA.
- Have stable disease activity as evidenced by no clinically meaningful change in immunomodulating or corticosteroid therapy in the past 1 month.
- Have moderate disease activity as reflected by a minimum of 3 swollen and tender joints.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Vanderbilt University Medical Center Coordinator of this site? Confirm its status | Nashville | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.