NCT03666845Completed
Plasma Ropivacaine Concentrations After Sciatic Nerve Block in Patients With Chronic Kidney Disease
Plasma Ropivacaine Concentrations After Peripheral Nerve Block in Patients With Severe Renal Dysfunction
Source: ClinicalTrials.gov · Last updated 25 Jan 2024
Brief summary (registry, in English)
This prospective observational study aimed to examine the pharmacokinetics of ropivacaine in patients with chronic kidney disease after sciatic nerve block. Sciatic nerve block for foot and ankle surgery will be performed using ropivacaine under ultrasound-guidance, and arterial blood test will be taken for total plasma ropivacaine concentration at 2.5, 5, 15, 30, 60 minutes and 2, 6, 24 hours after sciatic nerve block.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 5 (actual)
- First submitted
- 10 Sept 2018
- Start date
- 1 Oct 2019
- Primary completion date
- 21 Jul 2022
- Lead sponsor
- Seoul National University Hospital
- Diseases
- Chronic kidney disease
- NCT number
- NCT03666845
What you commit to
- Study type: Observational
- Participants enrolled: 5
- From 1 Oct 2019 to the primary completion date, 21 Jul 2022
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who need to renal replacement therapy, such as hemodialysis
- Patients with previous history of drug allery
Other illness
- Patients with allergic disease
Lab values
- Patients with liver disease (aspartate transaminase OR alanine transaminase \> 80 IU/L)
Other
- Patients with chronic pain persisting 3 months
Who the study is looking for
- Patients scheduled for foot and ankle surgery
- Patients with chronic kidney disease (glomerular filtration rate \< 60 ml/min/1.73m2) (changed from 30 ml/min/1.73m2 to facilitate patient recruitment)
- Patients who are thought to be clinically helpful to receive sciatic nerve block rather than general anesthesia because of comorbidities such as cardiopulmonary dysfunction and cerebral dysfunction
Age in the registry: 19 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Seoul National University Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.