NCT03671148RecruitingPhase 3
A Study Comparing Risankizumab to Placebo in Subjects with Active Psoriatic Arthritis Including Those Who Have a History of Inadequate Response or Intolerance to Biologic Therapy(ies) (KEEPsAKE 2)
A Phase 3, Randomized, Double-Blind Study Comparing Risankizumab to Placebo in Subjects with Active Psoriatic Arthritis Including Those Who Have a History of Inadequate Response or Intolerance to Biologic Therapy(ies) (KEEPsAKE 2)
Source: EU CTIS (euclinicaltrials.eu) · Last updated 3 Nov 2026
Brief summary (registry, in English)
To compare the efficacy of risankizumab 150 mg versus placebo for the treatment of signs and symptoms of PsA in the study population
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 133 (estimated)
- First submitted
- 19 Jan 2024
- Start date
- 18 Jun 2019
- Lead sponsor
- AbbVie Deutschland GmbH & Co. KG
- Diseases
- Psoriasis, Psoriatic arthritis
- NCT number
- NCT03671148
- EU CT number
- 2023-505477-33-00
- EudraCT number
- 2017-002464-40
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 133
- 27 sites in 10 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of EU CTIS (euclinicaltrials.eu). It describes the study, not your situation.
Who cannot take part
Copied verbatim from EU CTIS (euclinicaltrials.eu) and grouped by topic. Only the trial team decides who can take part.
Other illness
- Subject has a known hypersensitivity to risankizumab.
Other
- Subject is considered by investigator, for any reason, to be an unsuitable candidate for the study.
Who the study is looking for
- Clinical diagnosis of PsA with symptom onset at least 6 months prior to the Screening Visit and fulfillment of the Classification Criteria for PsA (CASPAR) at Screening Visit.
- Subject has active disease at Baseline
- Diagnosis of active plaque psoriasis with at least one psoriatic plaque of ≥ 2 centimeter (cm) diameter or nail changes consistent with psoriasis at Screening Visit.
- Subject has demonstrated an inadequate response or intolerance to biologic therapy(ies) or csDMARD therapy(ies).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (27)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universitair Ziekenhuis Gent Coordinator of this site? Confirm its status | Gent | Belgium | Active, not recruiting |
| UZ Leuven Coordinator of this site? Confirm its status | Leuven | Belgium | Active, not recruiting |
| MVZ Rheumatologie und Autoimmunmedizin Hamburg GmbH Coordinator of this site? Confirm its status | Hamburg | Germany | Completed |
| St. Elisabeth Gruppe GmbH Katholische Kliniken Rhein-Ruhr Coordinator of this site? Confirm its status | Herne | Germany | Completed |
| Frederiksberg Hospital Coordinator of this site? Confirm its status | Frederiksberg | Denmark | Recruiting |
| North Estonia Medical Centre Foundation Coordinator of this site? Confirm its status | Tallinn | Estonia | Active, not recruiting |
| East Tallinn Central Hospital Coordinator of this site? Confirm its status | Tallinn | Estonia | Active, not recruiting |
| MediTrials OÜ Coordinator of this site? Confirm its status | Tartu Linn | Estonia | Active, not recruiting |
| Complexo Hospitalario Universitario A Coruña Coordinator of this site? Confirm its status | A Coruña | Spain | Active, not recruiting |
| Hospital Universitario 12 de Octubre Coordinator of this site? Confirm its status | Madrid | Spain | Active, not recruiting |
| Parc Tauli Hospital Universitari Coordinator of this site? Confirm its status | Sabadell | Spain | Active, not recruiting |
| Hospital Universitario Y Politecnico La Fe Coordinator of this site? Confirm its status | Valencia | Spain | Active, not recruiting |
| Athens Naval Hospital Coordinator of this site? Confirm its status | Athens | Greece | Completed |
| University General Hospital of Heraklion Coordinator of this site? Confirm its status | Heraklion | Greece | Completed |
| Betegapolo Irgalmasrend Budai Irgalmasrendi Korhaz Coordinator of this site? Confirm its status | Budapest II | Hungary | Active, not recruiting |
| CRU Hungary Kft. Coordinator of this site? Confirm its status | Encs | Hungary | Active, not recruiting |
| University of Szeged Coordinator of this site? Confirm its status | Szeged | Hungary | Active, not recruiting |
| Vital-Medicina Kft. Coordinator of this site? Confirm its status | Veszprem | Hungary | Active, not recruiting |
| Azienda Ospedaliero-Universitaria delle Marche Coordinator of this site? Confirm its status | Ancona | Italy | Completed |
| Osteo-Medic S.C. Coordinator of this site? Confirm its status | Bialystok | Poland | Active, not recruiting |
| Malopolskie Centrum Kliniczne Coordinator of this site? Confirm its status | Cracow | Poland | Active, not recruiting |
| Centrum Kliniczno-Badawcze J.Brzezicki B.Gornikiewicz-Brzezicka Lekarze sp.p. Coordinator of this site? Confirm its status | Elblag | Poland | Active, not recruiting |
| Centrum Badan Klinicznych PI-House sp. z o.o. Coordinator of this site? Confirm its status | Gdansk | Poland | Active, not recruiting |
| Klinika Reuma Park Sp. z o.o. S.K. Coordinator of this site? Confirm its status | Warsaw | Poland | Active, not recruiting |
| Centro Hospitalar Universitario De Lisboa Norte E.P.E. Coordinator of this site? Confirm its status | Lisbon | Portugal | Active, not recruiting |
| Instituto Portugues de Reumatologia Coordinator of this site? Confirm its status | Lisbon | Portugal | Active, not recruiting |
| Unidade Local De Saude Do Alto Minho E.P.E. Coordinator of this site? Confirm its status | Ponte De Lima | Portugal | Active, not recruiting |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.