NCT03680781Completed
Accelerated Theta Burst in Treatment-Resistant Depression: A Dose Finding and Biomarker Study
Source: ClinicalTrials.gov · Last updated 22 Jul 2026
Brief summary (registry, in English)
This study evaluates the effectiveness of re-treatment using accelerated schedule of intermittent theta-burst stimulation for treatment-resistant depression. This is an open label study.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 40 (actual)
- First submitted
- 10 Sept 2018
- Start date
- 13 Apr 2018
- Primary completion date
- 2 Dec 2024
- Lead sponsor
- Stanford University
- Diseases
- Depression
- NCT number
- NCT03680781
What you commit to
- Study type: Interventional
- Participants enrolled: 40
- From 13 Apr 2018 to the primary completion date, 2 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of MI, CABG, CHF, or other cardiac history
- Any neurological conditions
- History of epilepsy
- Independent sleep disorder
- Autism Spectrum Disorder
Other
- OCD
Who the study is looking for
- Male or female, 18 to 75 years of age.
- Able to provide informed consent.
- Diagnosed with Major Depressive Disorder (MDD) or bipolar affective disorder 2 and currently experiencing a Major Depressive Episode (MDE).
- prior exposure to rTMS
- Participants must qualify as "moderate or severe treatment refractory" using the Maudsley staging method.
- Participants may continue antidepressant regimen, but must be stable for 6 weeks prior to enrollment in the study. They must maintain that same antidepressant regimen throughout the study duration.
- Participants are required to have a stable psychiatrist for the duration of study enrollment.
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine Coordinator of this site? Confirm its status | Palo Alto | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.