NCT03704350Active, not recruiting
Influence of Obesity on Endogenous Oxalate Synthesis
Source: ClinicalTrials.gov · Last updated 19 Mar 2026
Brief summary (registry, in English)
There is increasing evidence that obesity is associated with increased urinary oxalate excretion, an important risk factor for calcium oxalate stone formation. By the administration of a controlled low oxalate diet the investigators will estimate endogenous oxalate synthesis in both non-obese and obese non-kidney-stone forming adults. This study seeks to thusly increase the understanding of the relationships between obesity and endogenous oxalate synthesis to serve as a platform to develop novel therapies for stone prevention.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 3 Oct 2018
- Start date
- 24 May 2019
- Primary completion date
- 31 Aug 2026
- Lead sponsor
- University of Alabama at Birmingham
- Diseases
- Obesity
- NCT number
- NCT03704350
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 24 May 2019 to the primary completion date, 31 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- history of kidney stones
- history of diabetes, hepatic disease, renal disease including Chronic Kidney Disease (CKD), bowel disease or other endocrine disorders
Lab values
- hemoglobin A1C \> 6.5
Other
- pregnant or lactating women, or those with the intention to become pregnant in the near future
- abnormal liver enzymes
Who the study is looking for
- Age 25-60 years
- Body Mass Index (BMI) \<50
Age in the registry: 18 years to 60 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Alabama at Birmingham Coordinator of this site? Confirm its status | Birmingham | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.