NCT03729778Active, not recruitingEarly phase 1
Impact of HIV-1 and Aging on Mucosal Vaccine Responses
Source: ClinicalTrials.gov · Last updated 29 Jul 2026
Brief summary (registry, in English)
The purpose of this study is to learn more about both HIV-1 infection and advancing age, and their association with increased risk of serious infection and impaired response to the Prevnar 13 vaccine.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Early phase 1
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 16 Oct 2018
- Start date
- 18 Jan 2017
- Primary completion date
- 31 Mar 2020
- Lead sponsor
- VA Eastern Colorado Health Care System
- Diseases
- HIV
- NCT number
- NCT03729778
What you commit to
- Study type: Interventional · Early phase 1
- Planned participants: 100
- From 18 Jan 2017 to the primary completion date, 31 Mar 2020
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently taking: Corticosteroids (prednisone, medrol, etc), Chemotherapy, Immunosuppressive medication (cyclosporine, methotrexate, azathioprine, infliximab, adalimumab, rituximab, etanercept, etc), or illicit drugs (methamphetamine, cocaine, crack, or heroin)
Other illness
- Active liver disease
Lab values
- Chronic Kidney disease (creatinine ≥ 2.0 mg/dL)
Other
- Spleen removed
Who the study is looking for
- Veterans only (accessibility to non-veterans pending)
- Age 21-45 or 55-75 Years Old
- Have not received pneumococcal vaccine Prevnar PCV-13
- Able to attend 2-3 study visits over 1 month
- HIV+:
- -Undetectable Viral load
- HIV negative controls:
- -no history or risks for HIV infection
Age in the registry: 21 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rocky Mountain Regional VA Medical Center Coordinator of this site? Confirm its status | Aurora | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.