NCT03775980Completed
CIRSE Emprint Microwave Ablation Registry
Source: ClinicalTrials.gov · Last updated 13 May 2026
Brief summary (registry, in English)
Observation of the clinical use of the Emprint Microwave Ablation System for the ablation of Liver Metastases of Colorectal Adenocarcinoma.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 500 (actual)
- First submitted
- 11 Dec 2018
- Start date
- 4 Sept 2019
- Primary completion date
- 3 Jan 2023
- Lead sponsor
- Cardiovascular and Interventional Radiological Society of Europe
- Diseases
- Colorectal cancer
- NCT number
- NCT03775980
What you commit to
- Study type: Observational
- Participants enrolled: 500
- From 4 Sept 2019 to the primary completion date, 3 Jan 2023
- 38 sites in 13 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients receiving simultaneous bowel surgery and microwave ablation
- Patients receiving simultaneous IRE, RFA, SBRT, Cryoablation, HIFU or other local treatment than resection
Other illness
- Ongoing infection (viral/bacterial)
- Active cancers other than CRC
- Non-resected primary colon cancer
- Advanced liver disease or evidence of liver insufficiency
Other
- Life expectancy less than 6 months (palliative treatment)
- Extrahepatic metastases with the exception of a maximum of 5 lung nodules
- Pregnancy
- Patients with liver metastases that cannot be completely and safely treated
Who the study is looking for
- 18 years or older
- Proven colorectal liver metastases either histologically proven or diagnosed by imaging in a patient with known colorectal cancer
- Treated with the Emprint or Emprint HP Microwave ablation system
- Patient referred to MWA by a multidisciplinary tumour board
- Signed informed consent form
- Intention to completely treat (ablation, resection, SBRT) all visible disease within 8 weeks
- Maximum number of 9 total liver lesions
- All liver lesions must be local treatment-naive
- Maximum diameter of the largest liver lesion treated with MWA must not exceed 3cm
- Maximum diameter of lesions treated surgically may exceed this limitation
- Maximum number of 5 lung nodules eligible to be treated
- Patients may receive simultaneous liver resection and microwave ablation
- Patients may have received previous systemic therapy
- Patients must not have received surgical resection or thermal ablation for other liver lesions in the last 3 months before inclusion
- Patients treated with a liver-first approach may be included if treatment of the primary tumour is planned
- If applicable: complete response of treated rectal tumour proven by imaging
Age in the registry: 18 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (38)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| DRK Kliniken Berlin Westend Coordinator of this site? Confirm its status | Berlin | Germany | Unknown status |
| Vivantes Klinikum Neukölln Coordinator of this site? Confirm its status | Berlin | Germany | Unknown status |
| Charité Universitätsmedizin Berlin Coordinator of this site? Confirm its status | Berlin | Germany | Unknown status |
| Stadtisches Klinikum Braunschweig Coordinator of this site? Confirm its status | Braunschweig | Germany | Unknown status |
| Universitätsklinikum Carl Gustav Carus Dresden Coordinator of this site? Confirm its status | Dresden | Germany | Unknown status |
| Krankenhaus Nordwest Coordinator of this site? Confirm its status | Frankfurt | Germany | Unknown status |
| Universitätsklinikum Frankfurt Coordinator of this site? Confirm its status | Frankfurt | Germany | Unknown status |
| Medizinische Hochschule Hannover Coordinator of this site? Confirm its status | Hanover | Germany | Unknown status |
| SLK Kliniken Heilbronn Coordinator of this site? Confirm its status | Heilbronn | Germany | Unknown status |
| Krankenhaus Barmherzige Brüder München Coordinator of this site? Confirm its status | Munich | Germany | Unknown status |
| Universitätsklinikum Regensburg Coordinator of this site? Confirm its status | Regensburg | Germany | Unknown status |
| Tübingen University Hospital Coordinator of this site? Confirm its status | Tübingen | Germany | Unknown status |
| Aarhus University Hospital Coordinator of this site? Confirm its status | Aarhus | Denmark | Unknown status |
| Hospital Universitari de Bellvitge Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
| Hospital Universitario Ramón y Cajal Coordinator of this site? Confirm its status | Madrid | Spain | Unknown status |
| Hospital Universitario 12 de Octubre Coordinator of this site? Confirm its status | Madrid | Spain | Unknown status |
| University Hospital of Nimes Coordinator of this site? Confirm its status | Nîmes | France | Unknown status |
| CHU de Reims Coordinator of this site? Confirm its status | Reims | France | Unknown status |
| Les Hopitaux Universitaires de Strasbourg Coordinator of this site? Confirm its status | Strasbourg | France | Unknown status |
| Attikon University Athens Coordinator of this site? Confirm its status | Athens | Greece | Unknown status |
| University Hospital Centre Sisters of Mercy Coordinator of this site? Confirm its status | Zagreb | Croatia | Unknown status |
| Fondazione Poliambulanza Brescia Coordinator of this site? Confirm its status | Brescia | Italy | Unknown status |
| European Institute of Oncology Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| IRCCS San Giuseppe Multimedica Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| IRCCS Ospedale San Raffaele Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| Ospedaliero Universitaria San Luigi Gonzaga di Orbassano Coordinator of this site? Confirm its status | Orbassano | Italy | Unknown status |
| Ospedale Santissima Annunziata Coordinator of this site? Confirm its status | Taranto | Italy | Unknown status |
| Città della Salute e della scienza Torino Coordinator of this site? Confirm its status | Torino | Italy | Unknown status |
| Vilnius University Hospital Santaros Klinikos Coordinator of this site? Confirm its status | Vilnius | Lithuania | Unknown status |
| City General Hospital 8th September Coordinator of this site? Confirm its status | Skopje | North Macedonia | Unknown status |
| Amsterdam University Medical Center Coordinator of this site? Confirm its status | Amsterdam | Netherlands | Unknown status |
| Universitair Medisch Centrum Groningen Coordinator of this site? Confirm its status | Groningen | Netherlands | Unknown status |
| Leids Universitair Medisch Centrum Coordinator of this site? Confirm its status | Leiden | Netherlands | Unknown status |
| Oslo University Hospital Coordinator of this site? Confirm its status | Oslo | Norway | Unknown status |
| Centro Hospitalar Universitário de Lisboa Central Coordinator of this site? Confirm its status | Lisbon | Portugal | Unknown status |
| IPO Porto Coordinator of this site? Confirm its status | Porto | Portugal | Unknown status |
| Cukurova University Medical School Coordinator of this site? Confirm its status | Adana | Turkey (Türkiye) | Unknown status |
| Hacettepe University Hospital Coordinator of this site? Confirm its status | Ankara | Turkey (Türkiye) | Unknown status |
Related publications
- Results from the Pan-European CIEMAR study: Local Tumour Control After Microwave Ablation of Colorectal Liver Metastases and Exploratory Associations with Ablation Margins and Confirmation Software.Cardiovasc Intervent Radiol · 2026 · PMID 42701958
This page is information, not medical advice. Discuss any trial with your doctor.