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NCT03806283Recruiting

Mechanisms of Pregnancy Vascular Adaptations

Angiotensin 2 Receptor (AT2R) Expression/Activation in Endothelial Cells in Preeclampsia

Source: ClinicalTrials.gov · Last updated 20 Jan 2026

Brief summary (registry, in English)

The investigators will collect omental tissue (research surgical excision) and placental tissue (standard of care clinical delivery) from both preeclamptic and non-preeclamptic women during their c-section and use these samples to study the blood vessels, specifically the expression/activation of the AT2R.

Status (registry)
Recruiting
Study type
Observational
Enrollment
166 (estimated)
First submitted
14 Jan 2019
Start date
20 Nov 2018
Primary completion date
30 Apr 2027
Lead sponsor
University of Wisconsin, Madison
NCT number
NCT03806283

What you commit to

  • Study type: Observational
  • Planned participants: 166
  • From 20 Nov 2018 to the primary completion date, 30 Apr 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Undergoing cesarean section for placental abruption or bleeding complications.

Lab values

  • Treatment of severe hypertension by antihypertensive or use of magnesium sulfate after the patient is hospitalized for the diagnosis of preeclampsia.

Age

  • Singleton gestation not within 36 weeks, 0 days and 41 weeks, 0 days gestational age at the time of enrollment (delivery)

Other

  • Any major fetal structural anomalies or aneuploidies

Who the study is looking for

  • Female
  • Ages 18 to 40 years old
  • Singleton gestation between 28 weeks, 0 days and 41 weeks, 0 days gestational age at the time of consent
  • Undergoing caesarean section, either planned or otherwise with or without trial of labor

Age in the registry: 18 years to 40 years · Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
UnityPoint Health-Meriter Hospital
Coordinator of this site? Confirm its status
MadisonUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.