NCT03807128Recruiting
MYeloma Resistance And Clonal Evolution
Source: ClinicalTrials.gov · Last updated 14 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Multiple Myeloma (MM) is often associated with progression, temporary response to therapy and a high relapse rate over time resulting in a poor long-term prognosis. Because MM is classified as an incurable disease, therapeutic resistance is of great interest. However, knowledge about the biological mechanisms underlying resistance associated with MM therapies and about associated predictors remains poor. The MYRACLE cohort, a multicenter prospective cohort of patients with MM, is set up to address this limitation.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1400 (estimated)
- First submitted
- 26 Sept 2018
- Start date
- 11 Feb 2019
- Primary completion date
- 11 Feb 2034
- Lead sponsor
- Nantes University Hospital
- Diseases
- Multiple myeloma
- NCT number
- NCT03807128
What you commit to
- Study type: Observational
- Planned participants: 1400
- From 11 Feb 2019 to the primary completion date, 11 Feb 2034
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Minors
- Major under guardianship or curatorship
- Protected persons.
- Pregnant or breast-feeding women
- Persons benefiting from the AME
Who the study is looking for
- Patient consulting due to the discovery or recurrence of MM according to international diagnostic criteria (IMWG 2014)
- Patient having consented to participate in the study and his/her biocollection
- Patient affiliated to or benefiting from a social security scheme or similar
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| La Roche sur Yon Hospital Departmental Coordinator of this site? Confirm its status | La Roche-sur-Yon | France | Recruiting |
| Nantes University Hospital Coordinator of this site? Confirm its status | Nantes | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.