NCT03822572Active, not recruiting
ABCSG C08-Exercise II: Trial of Endurance Exercise Following Adjuvant Chemotherapy for Colorectal Cancer
ABCSG C08 - Exercise II: Randomized Trial of Endurance Exercise Following Adjuvant Chemotherapy for Colorectal Cancer
Source: ClinicalTrials.gov · Last updated 22 Jul 2026
Brief summary (registry, in English)
ABCSG C08 is a randomized, two-arm, multicenter trial to investigate the efficacy of endurance exercise following adjuvant chemotherapy in patients with colorectal cancer. Indication: Locally advanced colorectal cancer after adjuvant chemotherapy. Evidence supporting the beneficial effects of exercise programs during chemotherapy are available, the results across studies are not entirely consistent. Additional studies are needed to determine the optimal content, intensity, and form of training programs.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 92 (actual)
- First submitted
- 29 Nov 2018
- Start date
- 14 Feb 2019
- Primary completion date
- Jan 2028
- Lead sponsor
- Austrian Breast & Colorectal Cancer Study Group
- Diseases
- Colorectal cancer
- NCT number
- NCT03822572
What you commit to
- Study type: Interventional
- Participants enrolled: 92
- From 14 Feb 2019 to the primary completion date, Jan 2028
- 8 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- current study with chemotherapy or radiation
Other illness
- significant comorbid conditions precluding participation in a physical activity program (investigators decision)
- Regular (3-times a week) vigorous physical activity of \>150 minutes (type of physical activity: bicycling, cross walking (cross trainer), jogging, walking at a brisk pace, nordic walking, cross country skiing) within the last year before diagnosis of colorectal cancer
- past or current history of other malignant neoplasms other than colorectal cancer in the last 5 years except basal cell carcinoma of the skin and/or in situ carcinoma of the cervix
- clinically significant cardiovascular disease
Other
- disabled patients unable to participate in the physical activity program
- patients unwilling to complete endurance exercise or complete all questionnaires related to the study
- left bundle branch block
- current pregnancy or plans to become pregnant within the next 3 years
Who the study is looking for
- completely resected, histologically confirmed adenocarcinoma of the colon or rectum
- patients, who have completed adjuvant chemotherapy 4-16 weeks prior to randomization
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
- Age ≥18 years
- adequate hematologic functions \<=28d prior to randomization
- able to perform endurance exercise according to protocol
- ability to perform ergometry in order to assess physical capability at the discretion of the investigator
- signed informed consent prior to randomization
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (8)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| KH St. Josef Braunau Coordinator of this site? Confirm its status | Braunau am Inn | Austria | Unknown status |
| Med. Univ. Graz Coordinator of this site? Confirm its status | Graz | Austria | Unknown status |
| BKH Kufstein Coordinator of this site? Confirm its status | Kufstein | Austria | Unknown status |
| Kepler Universitätsklinikum Linz Coordinator of this site? Confirm its status | Linz | Austria | Unknown status |
| Hospital BHS Linz, Coop. Study Group Coordinator of this site? Confirm its status | Linz | Austria | Unknown status |
| LKH Salzburg-PMU, Univ. Klinik f. Innere Med III Coordinator of this site? Confirm its status | Salzburg | Austria | Unknown status |
| Pyhrn-Eisenwurzen Klinikum Steyr Coordinator of this site? Confirm its status | Steyr | Austria | Unknown status |
| Klinikum Wels-Grieskirchen Coordinator of this site? Confirm its status | Wels | Austria | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.