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NCT03823833Completed

Oocyte Freezing for Fertility Preservation in Benign Ovarian Tumors

Systematic Proposal of Fertility Preservation by Oocyte Freezing in Case of Benign Ovarian Tumors With High Risk of Recurrence

Source: ClinicalTrials.gov · Last updated 23 Dec 2025

Brief summary (registry, in English)

Benign ovarian cysts are frequent during women's life. They are diagnosed with pelvic pain or fortuitously during an ultra-sonographic exam. In case of persistence,a surgery will be necessary to identify the nature of the cyst and assess its benignity. In some case, cysts are recurrent and multiple surgeries are needed leading to a significant risk of ovarian damage by follicular depletion. Oocyte cryopreservation is no longer considered as an experimental technique of Fertility Preservation since 2013 as it has been recognized to be efficient and safe. According to reproductive medicine scientific committees and the French ethic law, fertility preservation has to be proposed in every situation of infertility risk. To date, there is no cohort study dedicated to fertility preservation by oocyte freezing in this specific subgroup of patients. The purpose of the study is to prospectively evaluate the oocyte number and quality after controlled ovarian hyperstimulation in patients with recurrent ovarian cysts.

Status (registry)
Completed
Study type
Observational
Enrollment
82 (actual)
First submitted
28 Jan 2019
Start date
28 Jul 2021
Primary completion date
4 Apr 2025
Lead sponsor
University Hospital, Lille
NCT number
NCT03823833

What you commit to

  • Study type: Observational
  • Participants enrolled: 82
  • From 28 Jul 2021 to the primary completion date, 4 Apr 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Personal history of thrombo-embolic events

Other

  • Borderline tumors
  • Undetectable AMH levels
  • pregnancy

Who the study is looking for

  • women with benign ovarian tumor with high risk of recurrence, i-e, endometrioma, dermoid cysts or mucinous cysts.
  • women with previous surgery and/or high risk of ovarian damage: bilateral cysts, cyst diameter higher than 5 cms
  • Having a social insurance
  • Able to give an informed consent

Age in the registry: 18 years to 35 years · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Hop Jeanne de Flandre Chu Lille
Coordinator of this site? Confirm its status
LilleFranceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.