NCT03825458Recruiting
Creation of a Cohort for the Quantitation and Characterization of Circulating Viral RNAs as a New Biomarker of Hepatitis B Functional Cure.
Source: ClinicalTrials.gov · Last updated 22 May 2026
Brief summary (registry, in English)
The " CirB-RNA " cohort aims to create a biological collection associated with clinical and biological data from patients with hepatitis B infection. This project is part of a much larger program that aims to characterize and quantify circulating viral RNAs as a possible new biomarker of hepatitis B functional cure.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 3500 (estimated)
- First submitted
- 31 Dec 2018
- Start date
- 25 Feb 2019
- Primary completion date
- 25 Jun 2029
- Lead sponsor
- Hospices Civils de Lyon
- Diseases
- Hepatitis B
- NCT number
- NCT03825458
What you commit to
- Study type: Observational
- Planned participants: 3500
- From 25 Feb 2019 to the primary completion date, 25 Jun 2029
- 6 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients participating at the time of the inclusion to an interventional trial evaluating a drug likely to interfere with this study.
Age
- Children less than 6 years old (in Lyon)
Other
- Persons deprived of their liberty by a judicial or administrative decision
- Adults who are subject to a legal protection measure
Who the study is looking for
- Adults patients and minor children over 6 years of age (in Lyon) with acute or chronic hepatitis B or presenting with HBsAg loss (with/without HBs seroconversion). (Co-infected patients with HDV and/or HCV and/or HIV are eligible)
- Patients requiring blood sampling for medical care at the time of the medical appointment.
- Informed patients who do not refuse to participate.
- Persons not affiliated to a social security scheme and persons receiving medical assistance from the state may be asked to participate in the study
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (6)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hôpital de la Croix-Rousse - Service de maladies infectieuses et tropicales Coordinator of this site? Confirm its status | Lyon | France | Recruiting |
| Hepatology department - Groupement Hospitalier Nord - Hôpital de la Croix-Rousse Coordinator of this site? Confirm its status | Lyon | France | Recruiting |
| Department of Hepato-gastroenterology and pediatric nutrition - Hôpital Femme-Mère Enfant Coordinator of this site? Confirm its status | Lyon | France | Recruiting |
| Gastroenterology and Hepatology department - • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Coordinator of this site? Confirm its status | Milan | Italy | Terminated |
| Gastroenterology and Hepatology department - • Università degli Studi di Palermo Coordinator of this site? Confirm its status | Palermo | Italy | Terminated |
| Infectious diseases and hepatology unit - Azienda Ospedaliero Coordinator of this site? Confirm its status | Parma | Italy | Terminated |
This page is information, not medical advice. Discuss any trial with your doctor.