NCT03845582CompletedPhase 2/3
Phase 2/3 Study of ALK-001 in Geographic Atrophy
A Phase 2/3 Multicenter, Randomized, Double-masked, Parallel-group, Placebo-controlled Study to Investigate the Safety, Pharmacokinetics, Tolerability, and Efficacy of ALK-001 in Geographic Atrophy Secondary to Age-related Macular Degeneration
Source: ClinicalTrials.gov · Last updated 3 Nov 2025
Brief summary (registry, in English)
This is a double-masked, multicenter, randomized, placebo-controlled clinical trial, evaluating the efficacy and safety of ALK-001 in participants with Geographic Atrophy (GA) secondary to age-related macular degeneration (AMD). Up to 200 participants will receive ALK-001 while up to 100 participants will receive a placebo.
- Status (registry)
- Completed
- Phase (registry)
- Phase 2/3
- Study type
- Interventional
- Enrollment
- 200 (actual)
- First submitted
- 15 Feb 2019
- Start date
- 7 May 2019
- Primary completion date
- 25 Jul 2023
- Lead sponsor
- Alkeus Pharmaceuticals, Inc.
- Diseases
- Macular degeneration
- NCT number
- NCT03845582
What you commit to
- Study type: Interventional · Phase 2/3
- Participants enrolled: 200
- From 7 May 2019 to the primary completion date, 25 Jul 2023
- 24 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Major Inclusion Criteria:
- \- At least one eye with geographic atrophy secondary to dry age-related macular degeneration (AMD)
- Major Exclusion Criteria:
- \- Medical condition, which may interfere with the progression of GA, prevent performance of study procedures, compliance with protocol, or continuous participation in the study
Age in the registry: 60 years to - · Sex: All · Does not accept healthy volunteers
Sites (24)
Sites in registry order. Pick your city on the disease page to sort them by distance.
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.