NCT03847714Completed
Probiotics in Dementia
Source: ClinicalTrials.gov · Last updated 12 Feb 2025
Brief summary (registry, in English)
Dementia is associated with changes in gut microbiome composition, gut barrier dysfunction, intestinal inflammation and systemic inflammation. Probiotics are a possibility to modulate the gut-brain axis. In this study the effect of probiotics on the gut microbiome and, gut barrier function, inflammation and cognitive dysfunction will be studied.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 17 (actual)
- First submitted
- 11 Feb 2019
- Start date
- 15 Jun 2019
- Primary completion date
- 31 Dec 2024
- Lead sponsor
- Medical University of Graz
- Diseases
- Alzheimer disease
- NCT number
- NCT03847714
What you commit to
- Study type: Interventional
- Participants enrolled: 17
- From 15 Jun 2019 to the primary completion date, 31 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Other forms of dementia
- Inflammatory bowel diseases
- Febrile illness within the last 4 weeks
- Acute hospital admission for dementia-unrelated reasons within the last 4 weeks
- Any other condition or circumstance, which, in the opinion of the investigator, would affect the patient's ability to participate in the protocol
Other
- Liver cirrhosis
- Antibiotic treatment within the last 4 weeks
- Dysphagia
Who the study is looking for
- Age \>18 years
- Dementia of Alzheimer type and mixed type (diagnosis by a board-certified neurologist/psychiatrist and according to ICD10)
- Mini Mental State Examination 21-26
- Stable treatment with anti-dementia drugs including phytotherapeutics (\>3 months) or no intention to start anti-dementia drugs
- Informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University Graz Coordinator of this site? Confirm its status | Graz | Austria | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.