NCT03859063Completed
Long-term Follow-up After Stroke (The LAST-long Trial)
A Multimodal Individualized Intervention to Prevent Functional Decline After Stroke. A Randomized Controlled Trial on Long-term Follow-up After Stroke (The LAST-long Trial)
Source: ClinicalTrials.gov · Last updated 16 Sept 2025
Brief summary (registry, in English)
Despite the improved treatment of acute stroke over the past decades, those suffering from stroke still are at an increased risk of functional and cognitive decline in the long term. The most common consequences of stroke are functional impairments, cognitive impairments, depression and fatigue. These are also regarded as barriers to achieve optimal adherence to the guidelines regarding secondary prevention. The primary aim of this project is to evaluate the effectiveness of a multimodal individualized intervention to prevent functional decline in the long term after stroke.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 301 (actual)
- First submitted
- 11 Feb 2019
- Start date
- 11 Apr 2019
- Primary completion date
- 30 Sept 2024
- Lead sponsor
- Norwegian University of Science and Technology
- Diseases
- Stroke
- NCT number
- NCT03859063
What you commit to
- Study type: Interventional
- Participants enrolled: 301
- From 11 Apr 2019 to the primary completion date, 30 Sept 2024
- 4 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Other serious diseases, judged by the medical doctor to make it difficult to comply with the intervention (i.e. serious neurological diseases or drug abuse).
Other
- Life expectancy \< 12 months
Who the study is looking for
- Diagnosis of first ever or recurrent stroke (ischemic stroke or hemorrhage)
- mRS \< 5
- Living in Trondheim, Skedsmo or Lørenskog municipality
- Less than 10 points on Short Physical Performance Battery (SPPB) OR less than 26 points on Montreal Cognitive Assessment (MoCA) OR more than 27 points on the 7 item version of the Fatigue Severity Scale (FSS-7) OR more than 7 points on the depression or anxiety items on Hospital Anxiety and Depression Scale (HADS) OR reduced hand function (i.e. fails on Motor Assessment Scale - Advanced arm- and hand function, item 3)
- Able to understand Norwegian
- Able and willing to sign informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (4)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ålesund Hospital Coordinator of this site? Confirm its status | Ålesund | Norway | Unknown status |
| Akershus University Hospital Coordinator of this site? Confirm its status | Lørenskog | Norway | Unknown status |
| Vestre Viken Bærum Hospital Coordinator of this site? Confirm its status | Sandvika | Norway | Unknown status |
| St. Olavs Hospital Stroke Unit Coordinator of this site? Confirm its status | Trondheim | Norway | Unknown status |
Related publications
- Impact of age and frailty on the effect of a multimodal individualized long-term intervention after stroke: the last-long trial.J Rehabil Med · 2026 · PMID 42929098
- A multimodal individualized long-term intervention to prevent functional decline after stroke (LAST-long): a single blinded randomised controlled trial.Lancet Reg Health Eur · 2026 · PMID 41323876
This page is information, not medical advice. Discuss any trial with your doctor.