NCT03864094CompletedPhase 4
Hemodynamics During Induction of General Anesthesia After Prophylactic Ephedrine, Phenylephrine or Norepinephrine.
"Haemodynamic Stability During Induction of General Anesthesia With Propofol and Remifentanil: A Randomized, Controlled, Double-blind Study Comparing Equipotent Prophylactic Doses of Ephedrine, Phenylephrine, Norepinephrine vs Placebo."
Source: ClinicalTrials.gov · Last updated 4 Oct 2024
Brief summary (registry, in English)
In this trial the investigators want to examine if there is any difference in hemodynamic stability when giving equipotent prophylactic injections of ephedrine 0,1 mg/kg, phenylephrine 1 microg/kg, norepinephrine 0,1 microg/kg or sodium chloride (NaCl) 9 mg/ml during induction of general anesthesia with propofol and remifentanil.
- Status (registry)
- Completed
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 128 (actual)
- First submitted
- 1 Mar 2019
- Start date
- 15 Mar 2022
- Primary completion date
- 14 Dec 2023
- Lead sponsor
- Helse Fonna
- Diseases
- Stroke
- NCT number
- NCT03864094
- EudraCT number
- 2019-000965-19
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 128
- From 15 Mar 2022 to the primary completion date, 14 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Pre-existing hypertension
- Diabetes for several years
- Ischemic heart disease
- Cerebrovascular disease
- Heart valve disease
- Verified cardiac arrhythmia
- Kidney or hepatic disease
- Hypersensitivity for soya, eggs or peanuts
Other
- Anaemia
- Pregnancy
- Poor health state
- Illicit substance use
- BMI \<20 or \>35 kg/m2
- SBP \>150 mmHg
- HR \>100 beats/min
Who the study is looking for
- Healthy women
- Age 18-50 years
- Gynecological procedures
- General anesthesia
Age in the registry: 18 years to 50 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Helse Fonna, Haugesund Sykehus Coordinator of this site? Confirm its status | Haugesund | Norway | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.