NCT03865914Recruiting
Correlation Study Between Clinical Phenotype and Pathology of Type 2 Diabetic Nephropathy
Source: ClinicalTrials.gov · Last updated 31 Mar 2022 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
With the rapid increase of diabetic nephropathy worldwide, type 2 diabetes mellitus(DM) is the leading cause of end-stage renal disease(ESRD). Pathological types of diabetic kidney disease(DKD) could be mainly divided into diabetic nephropathy（DN）and non-diabetic renal diseases（NDRD）. There are no accurate renal biopsy indications and standardized operation procedures for type 2 diabetic nephropathy. The clinical stages of type 2 diabetic nephropathy still referred to the Mogensen stage of type 1 diabetic nephropathy. Thus, our study aim to clarify the differences in clinical phenotype between type 2 DN and type 2 NDRD, analysis the correlation between clinical and pathological features, and offer the criteria for clinical staging and prognosis.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 2000 (estimated)
- First submitted
- 2 Mar 2019
- Start date
- 30 Nov 2017
- Primary completion date
- 30 Nov 2027
- Lead sponsor
- Chinese PLA General Hospital
- Diseases
- Chronic kidney disease
- NCT number
- NCT03865914
What you commit to
- Study type: Observational
- Planned participants: 2000
- From 30 Nov 2017 to the primary completion date, 30 Nov 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- The history of the disease was not complete
- Clinical diagnosed as other secondary renal diseases
- Patients with hereditary kidney disease
- Autoimmune diseases
- Patients with malignant tumor were expected to survive less than 6 months
Other
- Pregnancy and lactation
Who the study is looking for
- Age≥18, male or female
- Clinical diagnosed as type 2 diabetes mellitus
- The presence of renal impairment including: microalbuminuria or overt proteinuria or renal insufficiency
- The renal biopsy was performed with complete renal pathological diagnosis
- Obtaining the signed informed consent from patients
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chinese PLA General Hospital Coordinator of this site? Confirm its status | Beijing | China | Recruiting |
Related publications
- Clinical utility of BOLD-MRI in accurate diagnosis and prognostic evaluation of diabetic nephropathy: a prospective renal biopsy-based cohort study.Insights Imaging · 2026 · PMID 42008071
This page is information, not medical advice. Discuss any trial with your doctor.