NCT03878147Completed
Neurodevelopmental Assessment of Children in Uganda and Malawi Using a Software Package
Culture-Specific Neurodevelopmental Assessment of HIV-affected Children
Source: ClinicalTrials.gov · Last updated 20 Apr 2025
Brief summary (registry, in English)
The investigators will use Brain Power Games as a neurocognitive "stress test" or medical "challenge" test, in order to evaluate or improve brain/behavior functional integrity in HIV-affected children. This dual use of BPG is a key innovative feature. Each of the 5 core BPG games lasts 10 minutes and trains fine motor, monitoring/attention, visual/auditory working memory, spatial navigational learning. The investigator's central hypothesis is that the BPG performance gains will be improved compared to waitlist control for children in Uganda and Malawi.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 599 (actual)
- First submitted
- 12 Mar 2019
- Start date
- 30 Mar 2020
- Primary completion date
- 29 Feb 2024
- Lead sponsor
- Michigan State University
- NCT number
- NCT03878147
What you commit to
- Study type: Interventional
- Participants enrolled: 599
- From 30 Mar 2020 to the primary completion date, 29 Feb 2024
- 2 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Medical history of serious birth complications
- Other known brain injury or disorder requiring hospitalization
- Seizures or other neurological disabilities
Other
- Severe malnutrition
- Bacterial meningitis
- Encephalitis
- Cerebral malaria
Who the study is looking for
- HEU and HUU children at least 5 yrs of age and older from the PROMISE ND study (Uganda and Malawi)
- HIV+ children from P1104s (Uganda and Malawi)
- HUU children age-matched from PROMISE ND and P1104s study cohorts (Uganda and Malawi)
Age in the registry: 5 years to 12 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Johns Hopkins Research Project Coordinator of this site? Confirm its status | Blantyre | Malawi | Unknown status |
| Makerere University Johns Hopkins University Research Collaboration Coordinator of this site? Confirm its status | Kampala | Uganda | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.