NCT03920618Recruiting
Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF
Study on Three Types of Nucleotide/Nucleoside Analogues Treatment in Patients With Hepatitis b Virus Related Acute-on-chronic Liver Failure
Source: ClinicalTrials.gov · Last updated 29 Nov 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study is to investigate the clinical efficacy of three types of nucleotide/nucleoside analogues in treatment of HBV-related acute-on-chronic liver failure.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 16 Apr 2019
- Start date
- 21 Feb 2019
- Primary completion date
- 31 Dec 2024
- Lead sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
- Diseases
- Hepatitis B
- NCT number
- NCT03920618
What you commit to
- Study type: Interventional
- Planned participants: 150
- From 21 Feb 2019 to the primary completion date, 31 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Other active liver diseases;
- Hepatocellular carcinoma or other malignancy;
- Human immunodeficiency virus infection or congenital immune deficiency diseases;
- Severe diabetes, autoimmune diseases;
Other
- Pregnancy or lactation;
- Other important organ dysfunctions;
- Using glucocorticoid;
- Patients can not follow-up;
- Investigator considering inappropriate.
Who the study is looking for
- Positive hepatitis b surface antigen or hepatitis b virus DNA \> 0.5 year;
- Age from 12 to 65 years old;
- Serum total bilirubin level \> 10 times upper limit of normal;
- Prothrombin time activity \< 40% or prothrombin time international ratio \> 1.5；
- Do not receive nucleotide/nucleoside analogues treatment in the past half year.
Age in the registry: 12 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Third Affiliated Hospital of Sun Yat-sen University Coordinator of this site? Confirm its status | Guangzhou | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.