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NCT03921047Recruiting

Characterization of T-cell Repertoire in Patients With Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant

Characterization of T-cell Repertoire in Patients With AML Undergoing HSCT Through Next-Generation Sequencing of T Cell Receptor Alpha (TCRA) and T Cell Receptor Beta (TCRB) Genes

Source: ClinicalTrials.gov · Last updated 3 Jun 2026

Brief summary (registry, in English)

This research trial studies characterization of T-cell repertoire through next-generation sequencing in patients with acute myeloid leukemia undergoing stem cell transplant. Characterizing T-cell repertoire may help to understand if immune system plays a significant role in high risk patients with acute myeloid leukemia.

Status (registry)
Recruiting
Study type
Observational
Enrollment
250 (estimated)
First submitted
16 Apr 2019
Start date
12 Apr 2018
Primary completion date
31 Dec 2026
Lead sponsor
University of Southern California
NCT number
NCT03921047

What you commit to

  • Study type: Observational
  • Planned participants: 250
  • From 12 Apr 2018 to the primary completion date, 31 Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Inability to provide consent because of severe mental disorders

Other

  • Donor unwilling to provide consent

Who the study is looking for

  • Diagnosis of AML scheduled to undergo HSCT at University of Southern California (USC)

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
USC / Norris Comprehensive Cancer Center
Coordinator of this site? Confirm its status
Los AngelesUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.