NCT03922217Completed
e-Mindfulness for Depression in Older Adults
A Clinical Trial to Assess the Effect of Internet-delivered Mindfulness on Depressive Symptoms and Cognitive Function in Older Adults With Major Depression
Source: ClinicalTrials.gov · Last updated 24 Jul 2024
Brief summary (registry, in English)
This pilot study will test whether depression symptoms and cognitive functioning are impacted by internet-delivered mindfulness training following the principles of mindfulness meditation. The population is adults ages 65+ experiencing a current major depressive episode. Participants will receive an approximate 10-week instruction in mindfulness meditation, provided remotely through internet. Outcomes are depressive symptoms, assessed via clinical interview and self-report, and cognitive function, assessed via smartphone-delivered cognitive tests and surveys. The total duration of participation is approximately 18 weeks.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 31 (actual)
- First submitted
- 13 Mar 2019
- Start date
- 28 Mar 2019
- Primary completion date
- 5 Dec 2022
- Lead sponsor
- Washington University School of Medicine
- Diseases
- Depression
- NCT number
- NCT03922217
What you commit to
- Study type: Interventional
- Participants enrolled: 31
- From 28 Mar 2019 to the primary completion date, 5 Dec 2022
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Acutely suicidal or homicidal (i.e., in imminent danger with plan, urges and intent to harm oneself or others including any prior serious attempts (e.g., those requiring hospitalization) at the PI discretion
- Concurrent cognitive training, such as brain-training software, regular engagement in mindfulness practice and/or yoga x) significant neurological condition (e.g. stroke, seizure disorder, multiple sclerosis), that in the PI's judgment, could confound the interpretation of study results
Other illness
- Confirmed psychotic disorder, history of primary post-traumatic stress disorder
- Current or recent substance use disorder that according to the PI's judgement would confound the interpretation of the study results
- Any severe Axis II personality disorder or psychotic disorder that, in the PI's judgement, could confound diagnosis or adherence to treatment
- Unstable medical condition (e.g. uncontrolled diabetes mellitus or hypertension)
Other
- Meets DSM-V criteria for Mental Retardation
- Current incarceration
- Inability to cognitively manage the tasks required in this study
Who the study is looking for
- Males and females aged 65 or older
- DSM-V diagnosis of Major Depressive Disorder or Bipolar, Depressed type and experiencing depressive symptoms consistent with current major depressive episode
- Not currently psychotic and no history of psychosis within the previous 12 months; psychosis reported in the distant past may not be exclusionary if brief, per PI's judgment
- English speaking
- Able to give informed consent
- iOS smartphone user with internet access
- iOS operating system 6 or newer
- Internet access to view internet mindfulness course
Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Washington University School of Medicine, Health Mind Lab Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.