NCT03929432Active, not recruiting
Treatment Outcomes With tDCS in Post-Stroke Aphasia
Treatment Outcomes and Brain Mechanisms Associated With Non-Invasive Neuromodulation in Post-Stroke Aphasia
Source: ClinicalTrials.gov · Last updated 1 Jul 2026
Brief summary (registry, in English)
The purpose this study is to test the utility of pairing external neuromodulation with behavioral language treatment to boost therapy outcomes and to investigate the mechanisms associated with recovery. Because all PWA have word retrieval deficits, this project will test if greater language gains can be achieved by supplementing anomia intervention with excitatory brain stimulation to the left hemisphere and will evaluate associated functional brain changes to aid the optimization of neural reorganization to facilitate language processing.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 15 Apr 2019
- Start date
- 3 Sept 2019
- Primary completion date
- Aug 2028
- Lead sponsor
- University of Arkansas
- Diseases
- Stroke
- NCT number
- NCT03929432
What you commit to
- Study type: Interventional
- Planned participants: 50
- From 3 Sept 2019 to the primary completion date, Aug 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Co-occurring history of neurological disease/disorder/injury (e.g., traumatic brain injury, right hemisphere stroke, dementia)
- Co-occurring history of a major mental illness (e.g., schizophrenia, drug addiction, bipolar)
- Clinical conditions contraindicated for MRI or tDCS (e.g., implanted electrical devices, claustrophobia, seizure disorder)
Other
- Severe auditory comprehension deficits (determined by pretest) (i.e., global aphasia, Wernicke's aphasia, transcortical sensory aphasia)
- Inability to provide informed consent
- Positive pregnancy test (for females)
Who the study is looking for
- Presence of post-stroke aphasia
- Single left hemisphere stroke etiology
- At least 6 months post-stroke
- Age range between 18 and 80 years old
- Speak English as a native language
- Adequate hearing and vision to complete the tasks
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Arkansas for Medical Sciences Coordinator of this site? Confirm its status | Little Rock | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.