NCT03931109Completed
Circulating miRNA in Primary Hyperparathyroidism
Circulating microRNA Signatures in Primary Hyperparathyroidism
Source: ClinicalTrials.gov · Last updated 1 Aug 2024
Brief summary (registry, in English)
The goal of this study is to: 1. Analyze the expression levels of circulating (serum) miRNAs in primary hyperparathyroidism patients with and without osteoporosis, and patients with osteoporosis undergoing thyroidectomy, and to correlate with clinical markers of bone remodeling including biochemical and radiologic studies. 2. To evaluate serum miRNA levels after treatment with parathyroidectomy.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 96 (actual)
- First submitted
- 15 Apr 2019
- Start date
- 7 Sept 2018
- Primary completion date
- 1 Jul 2024
- Lead sponsor
- University of Pennsylvania
- Diseases
- Osteoporosis
- NCT number
- NCT03931109
What you commit to
- Study type: Observational
- Participants enrolled: 96
- From 7 Sept 2018 to the primary completion date, 1 Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- prior parathyroidectomy
- currently taking steroids or has been on steroids for more than 7 days in the last two years
- estrogen therapy within the last two years
- bisphosphonate therapy within the last two years
Other illness
- history of ESRD on dialysis or renal osteodystrophy
- diagnosis of Cushing's disease or Cushing's syndrome
Other
- hyper or hypothyroid by TSH
- taking biotin within 24 hours of blood draw
Who the study is looking for
- post menopausal
- has had DXA scan
- has 24 hr Urine Calcium
- Elevated serum calcium
- Vitamin D above 20 ng/ml
- capable of giving informed consent
- female
- indication for biochemical primary hyperparathyroidism or an indication for partial or total thyroidectomy
Age in the registry: 50 years to 100 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Perelman Center for Advanced Medicine/ Hospital of the University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.