NCT03933384RecruitingPhase 4
Tenofovir Alafenamide Versus Entecavir for the Treatment of Chronic Hepatitis B
Tenofovir Alafenamide Versus Entecavir for the Treatment of Chronic Hepatitis B: An Open Label, Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 14 May 2026
Brief summary (registry, in English)
To compare the efficacy and renal safety of tenofovir alafenamide (TAF) versus entecavir (ETV) in the chronic hepatitis B patients.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 140 (estimated)
- First submitted
- 28 Apr 2019
- Start date
- 19 Aug 2019
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Taichung Veterans General Hospital
- Diseases
- Hepatitis B
- NCT number
- NCT03933384
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 140
- From 19 Aug 2019 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior use of nucleot(s)ide analogues for chronic hepatitis B
- Prior use of interferon for chronic hepatitis B within six months
- Concurrent other uncontrolled malignancy
Other illness
- Decompensated liver disease (Child-Pugh B \&C)
- End stage renal disease (eGRF \< 15 ml/min/1.73m2)
- Known history of human immunodeficiency virus or hepatitis C virus co-infection
Other
- Women in pregnancy or lactation
- Cannot conform to the study protocol of this study
Who the study is looking for
- Patients more than 20 years old
- Chronic hepatitis B patients
- Patients who were indicated for hepatitis B virus antiviral therapy
Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Taichung Veterans General Hospital Coordinator of this site? Confirm its status | Taichung | Taiwan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.