NCT03934866Active, not recruiting
The SUMMIT Study: A Cancer Screening Study
The SUMMIT Study: Cancer Screening Study With or Without Low Dose Lung CT to Validate a Multi-cancer Early Detection Test
Source: ClinicalTrials.gov · Last updated 5 Dec 2024
Brief summary (registry, in English)
The SUMMIT Study will enrol 13,000 participants in order to investigate how cancer screening can be improved and delivered. The SUMMIT Study has two main aims: the first is to clinically validate a blood test for detecting multiple cancers at an early stage. The second is to examine the feasibility of delivering a low-dose CT (LDCT) screening service for lung cancer to a high-risk population in North Central and East London.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 13035 (actual)
- First submitted
- 26 Apr 2019
- Start date
- 8 Apr 2019
- Primary completion date
- May 2025
- Lead sponsor
- University College, London
- Diseases
- Lung cancer
- NCT number
- NCT03934866
What you commit to
- Study type: Observational
- Participants enrolled: 13035
- From 8 Apr 2019 to the primary completion date, May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently receiving treatment (e.g., chemotherapy, radiotherapy, watchful waiting) for an active cancer. If on adjuvant hormonal therapy can be included (e.g. for breast and prostate cancer).
Who the study is looking for
- Individuals 55 to 77 years old at the time of GP data extraction, who meet either of the following criteria:
- USPSTF LDCT screening criteria: a history of at least 30 pack years of smoking and if a former smoker, have quit in the past 15 years; or
- PLCOm2012 6-year lung cancer risk of ≥1.3%
- Capable of providing informed consent and willing to comply with all parts of the protocol
Age in the registry: 55 years to 77 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UCLH Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
Related publications
- Upstaging of screen-detected lung cancers during diagnostic assessment.Thorax · 2026 · PMID 41629156
- The effect of cigar, cigarillo and pipe smoking on lung cancer risk and screening eligibility.Br J Cancer · 2026 · PMID 42567897
This page is information, not medical advice. Discuss any trial with your doctor.