NCT03967080Completed
Adaptive Radiotherapy for High-risk Prostate Cancer Using Multiparametric MRI
Adaptive Radiotherapy for High-risk Prostate Cancer Using Multiparametric MRI (ARPC-MRI) - a Feasibility Study
Source: ClinicalTrials.gov · Last updated 3 Sept 2025
Brief summary (registry, in English)
This small study will investigate the feasibility of using multi-parametric MRI to introduce and support adaptive radiotherapy treatments for high-risk prostate cancer.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 5 (actual)
- First submitted
- 22 May 2019
- Start date
- 5 Feb 2019
- Primary completion date
- 1 Sept 2024
- Lead sponsor
- East and North Hertfordshire NHS Trust
- Diseases
- Prostate cancer
- NCT number
- NCT03967080
What you commit to
- Study type: Observational
- Participants enrolled: 5
- From 5 Feb 2019 to the primary completion date, 1 Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who are not due to receive androgen deprivation therapy (ADT)
- Previous radiotherapy to the pelvis
Other
- Any contraindication to MRI scanning including contraindication to MRI contrast agents
- Any physical or social reasons that would make attendance for additional visits impossible.
- Any patient with or planned for prostate fiducial markers.
- Unable to give informed consent.
- Patients currently enrolled in an interventional clinical trial.
Who the study is looking for
- New diagnosis of high-risk prostate cancer: any of:
- Gleason score of 8, 9 or 10
- PSA \> 20
- T3/4
- Patient due to receive androgen deprivation therapy (ADT)
- Prescribed 78Gy/39# external beam radiotherapy
- Measurable dominant intraprostatic tumour on diagnostic imaging of at least 10mm diameter
- ≥18 years of age
- ECOG performance status of 0-1
- Informed, written and witnessed consent to participate is required.
Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| East and North Hertfordshire NHS Trust Coordinator of this site? Confirm its status | Northwood | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.