NCT03974997Recruiting
TWEAK, a New Biomarker for Predicting Inflammatory Relapses in Multiple Sclerosis
TNF-related Weak Inducer of Apoptosis (TWEAK), a New Biomarker Predicting Inflammatory Thrust in Multiple Sclerosis
Source: ClinicalTrials.gov · Last updated 23 Sept 2026
Brief summary (registry, in English)
A significant variation in the serum concentration of the circulating cytokine TWEAK is associated with the onset of an inflammatory attack of MS. Study the concentration variations of the serum soluble form of cytokine TWEAK during the first year of MS and to analyze their correlation with the occurrence of an inflammatory disease outbreak.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 3 Jun 2019
- Start date
- 16 Jun 2023
- Primary completion date
- 16 Jun 2027
- Lead sponsor
- Assistance Publique Hopitaux De Marseille
- Diseases
- Multiple sclerosis
- NCT number
- NCT03974997
What you commit to
- Study type: Interventional
- Planned participants: 50
- From 16 Jun 2023 to the primary completion date, 16 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- age \<18 years old
Other
- person in an emergency situation
- adult who is subject to a legal protection measure (an adult under guardianship, conservatorship, or judicial protection), or who is unable to give consent
- not Enrolled in a Social Security Program
- pregnant or breastfeeding woman
Who the study is looking for
- a first episode of inflammation and demyelination of the central nervous system affecting the optic nerve, the spinal cord, one cerebral hemisphere, or the brainstem; or confirmed multiple sclerosis
- no differential diagnosis at enrollment based on clinical examination and laboratory tests
- compliance with the revised 2017 Mac Donald diagnostic criteria
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Assistance Publique Hôpitaux de Marseille Coordinator of this site? Confirm its status | Marseille | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.