NCT03976921Active, not recruiting
Impact of Stress CT Myocardial Perfusion on Downstream Resources and Prognosis
Impact of Stress Cardiac Computed Tomography Myocardial Perfusion on Downstream Resources and PROgnosis in Patients With Suspected or Known Coronary Artery Disease: a Multicenter International Study
Source: ClinicalTrials.gov · Last updated 3 Jun 2026
Brief summary (registry, in English)
CT myocardial perfusion imaging (CTP) represents one of the newly developed CT-based techniques but its cost-effectiveness in the clinical pathway is undefined. The aim of the study is to evaluate the usefulness of combined evaluation of coronary anatomy and myocardial perfusion in intermediate to high-risk patients for suspected CAD or with known disease in terms of clinical decision-making, resource utilization and outcomes in a broad variety of geographic areas and patient subgroups.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 2000 (estimated)
- First submitted
- 30 May 2019
- Start date
- 1 Jul 2019
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- Centro Cardiologico Monzino
- Diseases
- Coronary artery disease
- NCT number
- NCT03976921
What you commit to
- Study type: Interventional
- Planned participants: 2000
- From 1 Jul 2019 to the primary completion date, 30 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Performance of any non-invasive diagnostic testing within 90 days before enrollment
Other illness
- Acute coronary syndrome
- Cardiac arrhythmias
- Structural cardiomyopathy outside of suspected or know ischemic heart disease
Other
- Low to intermediate pre-test likelihood of CAD according to the updated Diamond-Forrester risk model score
- Need for an emergent procedure
- Evidence of clinical instability
- Contra-indication to contrast agent administration and/or impaired renal function
- Inability to sustain a breath hold
- Pregnancy
- Presence of pace maker or implantable cardioverter defibrillator
- Contra-indications to the administration of sub-lingual nitrates, beta-blockade and adenosine
Who the study is looking for
- Consecutive patients (age ≥ 18 years) with known or suspected CAD referred for clinically indicated diagnostic evaluation.
- CCTA has to be performed with the state of art in terms of scanner technology as follow: Revolution CT (GE Healthcare, Milwaukee, WI), CardioGraphe (Arineta, Caesarea, Israel), SOMATOM Force (Siemens, Forchheim, Germany), Brilliance iCT and IQon CT (Philips, Best, Netherlands), Aquilion One Vision (Toshiba Medical Systems Corp., Otawara, Japan).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centro Cardiologico Monzino IRCCS Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.