NCT03978936Completed
Medication Adherence With Telehealthcare Medication Therapy Management
Improving Medication Adherence With Telehealthcare Medication Therapy Management to Change Health Outcomes in Adolescents and Young Adults With Asthma
Source: ClinicalTrials.gov · Last updated 26 Jun 2026
Brief summary (registry, in English)
Improving Medication Adherence with Telehealthcare Medication Therapy Management to Change Health Outcomes in Adolescents and Young Adults with Asthma (MATCH) is a multi-center, randomized parallel group study targeted to an at-risk population of Adolescents and Young Adults (AYA) with uncontrolled asthma who have poor adherence with prescribed Inhaled corticosteroid (ICS) therapy.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 375 (actual)
- First submitted
- 5 Jun 2019
- Start date
- 18 Nov 2019
- Primary completion date
- 14 Mar 2025
- Lead sponsor
- Johns Hopkins University
- Diseases
- Asthma
- NCT number
- NCT03978936
What you commit to
- Study type: Interventional
- Participants enrolled: 375
- From 18 Nov 2019 to the primary completion date, 14 Mar 2025
- 21 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of an investigational treatment in the previous 30 days.
- Previous enrollment in MATCH Structured Interviews ( Aim 1)
Other illness
- Any condition(s) in the opinion of the physician that puts the participant at risk from participating in the study
Other
- Currently enrolled in an intervention trial
- Currently uses an ICS not compatible with the Propeller sensor
- Inability to comply with study procedures, including:
- Inability or unwillingness to provide informed consent (or assent in the case of a minor).
- Inability to perform study measurements.
- inability to be contacted by phone via calls and /or text messaging
- Not willing to have video chat
Who the study is looking for
- Age 12 through 35 years
- Speaks English or Spanish
- Physician diagnosed asthma (without any other co-morbid pulmonary disease)
- Prescribed ICS treatment for at least 3 months prior to screening
- Adherence to Refills and Medication Scale (ARMS) 7-item questionnaire score of \>8 (low or moderate adherence)
- Current use of albuterol metered dose inhaler (MDI) for rescue: ProAir, Ventolin, albuterol sulfate (from Prasco or Teva)
- Uncontrolled asthma:
- Symptomatic asthma defined as 3 of the following in the past 4 weeks:
- Daytime symptoms of asthma more than twice per week
- Any night awakening due to asthma
- Rescue inhaler use for symptoms more than twice per week
- Any activity limitation due to asthma; OR
- Asthma Control Test score ≤19
- Has iPhone or Android smart phone with Short Message Service (SMS)
- Has access to reliable WiFi service and a device with capability for telemedicine study visits
- Ability to understand and willingness to sign consent documents
- Evidence of Propeller sensor connection in the 4-week run-in period
Age in the registry: 12 years to 35 years · Sex: All · Does not accept healthy volunteers
Sites (21)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Michigan Coordinator of this site? Confirm its status | Ann Arbor | United States | Unknown status |
| University of Alabama at Birmingham Coordinator of this site? Confirm its status | Birmingham | United States | Unknown status |
| University of Chicago Hospitals Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
| Northwestern University Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
| University of Illinois at Chicago Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
| Rush University Medical Center Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
| Vermont Lung Center at The University of Vermont Coordinator of this site? Confirm its status | Colchester | United States | Unknown status |
| National Jewish Medical and Research Center Coordinator of this site? Confirm its status | Denver | United States | Unknown status |
| Duke University Medical Center Coordinator of this site? Confirm its status | Durham | United States | Unknown status |
| Baylor College of Medicine Coordinator of this site? Confirm its status | Houston | United States | Unknown status |
| Nemours Children's Specialty Care Coordinator of this site? Confirm its status | Jacksonville | United States | Unknown status |
| University of Florida - College of Medicine Coordinator of this site? Confirm its status | Jacksonville | United States | Unknown status |
| Children's Mercy Hospital Coordinator of this site? Confirm its status | Kansas City | United States | Unknown status |
| University of Kansas Medical Center Coordinator of this site? Confirm its status | Kansas City | United States | Unknown status |
| New York University School of Medicine Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| Mount Sinai National Jewish Health Respiratory Institute; Icahn School of Medicine Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| Columbia University Medical Center Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| Temple University Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
| University of California at San Francisco Coordinator of this site? Confirm its status | San Francisco | United States | Unknown status |
| Pacific Northwest Airways - VA Puget Sound Healthcare System Coordinator of this site? Confirm its status | Seattle | United States | Unknown status |
| University of Arizona Coordinator of this site? Confirm its status | Tucson | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.