NCT03999138Recruiting
MRI Assessment of Pulmonary Edema in Acute Heart Failure
Source: ClinicalTrials.gov · Last updated 8 May 2026
Brief summary (registry, in English)
Researchers are testing a more accurate way to measure how much fluid is in the lungs (also called pulmonary edema, or "increased lung water") in people with Heart Failure (HF) using MRI (Magnetic Resonance Imaging). There is little known about the exact level of lung water in patients with AHF or how these levels change from the time of hospital admission to discharge. The purpose of this research study is to measure the lung water in patients hospitalized for HF, to determine the change in lung water over the course of hospitalization and treatment, and to find out if lung water levels can predict if patients are higher or lower risk for returning to the hospital or dying from heart failure.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 22 May 2019
- Start date
- 2 Jan 2019
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- University of Alberta
- Diseases
- Heart failure
- NCT number
- NCT03999138
What you commit to
- Study type: Observational
- Planned participants: 300
- From 2 Jan 2019 to the primary completion date, 31 Dec 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- moderate to severe dementia
Other
- contraindication to MRI
- patient too critically ill/unstable as per the clinical care team for transport to MRI scanner within the required scanning window
Who the study is looking for
- 18 years of age or older and willing/able to provide informed consent
- patients being treated for acute heart failure (including those patients with both reduced and preserved ejection fraction)
- patients receiving medical therapy for pulmonary edema by current standard of care (including oral or IV diuretics)
- patients identified within 48 hours of initiation of medical therapy for pulmonary edema, defined as the time of first diuretic (IV or PO) or escalation of existing diuretic therapy administered within the ED or hospital
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Alberta Coordinator of this site? Confirm its status | Edmonton | Canada | Active, not recruiting |
| University of Ottawa Heart Institute Coordinator of this site? Confirm its status | Ottawa | Canada | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.