NCT04000971Completed
Coordinated, Collaborative, Comprehensive, Family-based, Integrated, Technology-enabled Stroke Care
C3FIT (Coordinated, Collaborative, Comprehensive, Family-based, Integrated, Technology-enabled Care): A Randomized Trial for Stroke
Source: ClinicalTrials.gov · Last updated 15 May 2026
Brief summary (registry, in English)
Stroke is the 5th leading cause of death and the leading cause of adult disability in the United States (US). Stroke is a complex disease with multiple interacting risk factors (including genetic, high blood pressure and cholesterol, and lifestyle factors like smoking, diet, and exercise) that lead to initial and recurrent stroke. Up to 90% of stroke survivors have some functional deficit that impacts both physical and mental health.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 1196 (actual)
- First submitted
- 25 Jun 2019
- Start date
- 25 Feb 2020
- Primary completion date
- 30 Sept 2024
- Lead sponsor
- Vanderbilt University Medical Center
- Diseases
- Stroke
- NCT number
- NCT04000971
What you commit to
- Study type: Interventional
- Participants enrolled: 1196
- From 25 Feb 2020 to the primary completion date, 30 Sept 2024
- 21 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with a planned admission to hospice care prior to consent.
Other illness
- Clinical transient ischemic attack (TIA)38-41 is excluded even if there is a computerized tomography (CT) or magnetic resonance imaging (MRI) lesion corresponding to the clinical syndrome at presentation.
- Patients not anticipated to survive for 1-year due to neurological or other medical status (i.e., advanced cancer, hospice care, heart disease, etc.).
Other
- Already enrolled or planned enrollment in another clinical trial for which participation in C3FIT would be compromised with regard to follow-up assessment of outcomes or continuation in C3FIT.
- Patients who in the opinion of the site investigator cannot be involved in follow up care.
- Inability or unwillingness of subject or legal guardian/representative to understand and cooperate with study procedures or provide informed consent.
Who the study is looking for
- Age 18+.
- Clinical diagnosis of acute stroke with brain imaging compatible with intracerebral hemorrhage or ischemic stroke (including normal brain scan); see International Classification of Disease 10 (ICD 10) codes.
- English or Spanish speaking subjects.
- Patient admitted within 7 days of their index stroke event.
- Patient is discharged alive and not to hospice care.
- Patient living at discharge within the geography of recruitment for that C3FIT site.
- Pre-morbid Modified Rankin Score (mRS) score of 0-1.
- Patient and/or surrogate give consent to participate after an informed consent process.
- Patients who go to rehabilitation inpatient therapy or other care facilities are eligible, as long as they reside in the geographic are of recruitment and do not go to hospice care.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (21)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of New Mexico Health Sciences Center Coordinator of this site? Confirm its status | Albuquerque | United States | Unknown status |
| Emory University/Grady Health Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
| Augusta University Medical Center Coordinator of this site? Confirm its status | Augusta | United States | Unknown status |
| University of Alabama at Birmingham Coordinator of this site? Confirm its status | Birmingham | United States | Unknown status |
| Medical University of South Carolina Coordinator of this site? Confirm its status | Charleston | United States | Unknown status |
| Northwestern University Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
| Ohio Health Riverside Methodist Hospital Coordinator of this site? Confirm its status | Columbus | United States | Unknown status |
| Doctors Hospital Renaissance Coordinator of this site? Confirm its status | Edinburg | United States | Unknown status |
| Hartford Hospital Coordinator of this site? Confirm its status | Hartford | United States | Unknown status |
| Mayo Clinic Coordinator of this site? Confirm its status | Jacksonville | United States | Unknown status |
| Johnson City Medical Center at Ballad Health Coordinator of this site? Confirm its status | Johnson City | United States | Unknown status |
| University of Kansas Medical Center Coordinator of this site? Confirm its status | Kansas City | United States | Unknown status |
| Covenant Health Fort Sanders Regional Medical Center Coordinator of this site? Confirm its status | Knoxville | United States | Unknown status |
| Intermountain Coordinator of this site? Confirm its status | Las Vegas | United States | Unknown status |
| University of Louisville Hospital Coordinator of this site? Confirm its status | Louisville | United States | Unknown status |
| University of Wisconsin - Madison Coordinator of this site? Confirm its status | Madison | United States | Unknown status |
| Baptist Memorial Hospital Coordinator of this site? Confirm its status | Memphis | United States | Unknown status |
| Vanderbilt University Medical Center Coordinator of this site? Confirm its status | Nashville | United States | Unknown status |
| Mayo Clinic Hospital Coordinator of this site? Confirm its status | Phoenix | United States | Unknown status |
| University of Pittsburgh Medical Center Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
| Penn State Coordinator of this site? Confirm its status | State College | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.