NCT04002362CompletedPhase 2
Symptom Clusters in Children With Exacerbation-prone Asthma
Source: ClinicalTrials.gov · Last updated 13 Feb 2026
Brief summary (registry, in English)
Pediatric participants with exacerbation-prone asthma will receive an intramuscular injection of triamcinolone acetonide and will be followed for 48 weeks. The study visit 2 weeks after the injection will assess the response to the study medication, while the remaining study visits will examine the temporal stability of the symptom clusters.
- Status (registry)
- Completed
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 68 (actual)
- First submitted
- 27 Jun 2019
- Start date
- 13 Nov 2019
- Primary completion date
- 16 Jan 2025
- Lead sponsor
- Emory University
- Diseases
- Asthma
- NCT number
- NCT04002362
What you commit to
- Study type: Interventional · Phase 2
- Participants enrolled: 68
- From 13 Nov 2019 to the primary completion date, 16 Jan 2025
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous allergic reaction to systemic corticosteroids
Other illness
- Hepatic, biliary, or renal disease that can interfere with drug metabolism/excretion
- Chronic medical disorders that may increase the risk of drug-related injury, including osteogenesis imperfecta (increased risk of fracture with corticosteroids), or Crohn's disease, ulcerative colitis, juvenile rheumatoid arthritis, clotting disorders, or Factor deficiency (increased risk of bleeding with corticosteroid therapy)
- Congenital disorders or deformities of the chest wall, lungs or airways
- History of premature birth \<35 weeks gestation
Other
- Pregnancy
- Current smoking
- Unwillingness to receive triamcinolone
- Planning to relocate before study completion
Who the study is looking for
- Age 6 to less than 21 years at the enrollment visit
- Physician diagnosis of asthma
- History of an asthma exacerbation in the previous 12 months, defined as either:
- Treatment with systemic corticosteroids, or
- Increase in rescue medication use (i.e., albuterol or inhaled corticosteroid) for 24 hours or more, or
- One or more missed school days due to asthma symptoms, or
- An unscheduled visit for asthma at either a physician's office, urgent care, hospital emergency room, or
- Hospitalization for asthma
Age in the registry: 6 years to 21 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Children's Healthcare of Altanta Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
| Emory Children's Center Coordinator of this site? Confirm its status | Atlanta | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.