NCT04018391Completed
Task Shifting to Treat Depression and HIV Medication Nonadherence in Low Resource Settings
The TENDAI Study: Task Shifting to Treat Depression and HIV Medication Nonadherence in Low Resource Settings
Source: ClinicalTrials.gov · Last updated 29 May 2026
Brief summary (registry, in English)
A hybrid effectiveness-efficacy trial to evaluate a stepped care task shifted intervention to treat depression and HIV medication nonadherence in low resource settings in rural Zimbabwe.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 280 (actual)
- First submitted
- 2 Jul 2019
- Start date
- 12 Jul 2019
- Primary completion date
- 31 May 2024
- Lead sponsor
- King's College London
- Diseases
- HIV
- NCT number
- NCT04018391
What you commit to
- Study type: Interventional
- Participants enrolled: 280
- From 12 Jul 2019 to the primary completion date, 31 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Has ever received PST or CBT for depression
Other illness
- Active major mental illness (e.g. untreated psychosis or mania, actively suicidal), major untreated or undertreated mental illness or advanced physical disease or severe cognitive impairment assessed using the psychosis module of the MINI, the PHQ-9, and the International HIV dementia Scale which would interfere with engagement in PST-AD
Age
- Less than 18 years of age
Other
- Unable to provide informed consent
Who the study is looking for
- Initiated on ART for at least 6 months
- Clinically significant depression symptoms scoring \>/= 10 on the Patient Health Questionnaire-9
- Viral non-suppression in past two months per local clinic standard (VL \> 1000 copies/mL)
- Able to provide informed consent
- If prescribed antidepressants, on stable regimen for at least 2 months
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Marondera Provincial Hospital Coordinator of this site? Confirm its status | Marondera | Zimbabwe | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.