NCT04024631Recruiting
Phenotyping Genetic Risk for Type 2 Diabetes
Phenotyping Children and Adults With Possible High or Low Genetic Risk for Type 2 Diabetes
Source: ClinicalTrials.gov · Last updated 21 Sept 2026
Brief summary (registry, in English)
This study tests the hypothesis that non-diabetic individuals with a high genetic risk score for type 2 diabetes have impaired glucose tolerance and insulin resistance compared to those with a low genetic risk score for type 2 diabetes.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 13 Jul 2019
- Start date
- 17 Jun 2019
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- University of Pennsylvania
- Diseases
- Type 2 diabetes
- NCT number
- NCT04024631
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 17 Jun 2019 to the primary completion date, 30 Jun 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- prior diagnosis of type 1, type 2, or secondary diabetes
- recent systemic chemotherapy use
Other illness
- hypothalamic obesity or related genetic disorder of metabolism
- gastrointestinal impairment or surgery that may impact absorption
- major organ system illness or any underlying condition requiring regular medication or treatment that could make implementation of the protocol or interpretation of the study results difficult
Lab values
- use of medications that would impact glucose and insulin response such as steroids, metformin or other anti-diabetic medication
- acute illness that may impact insulin and glucose dynamics
Other
- pregnancy
- anemia
- inability to comply with study protocol
Who the study is looking for
- Age 10-70 years
- Prior participant of the UPenn Biobank or Center for Applied Genomics Biobank and agreed to be recontacted for future research.
- Adults with BMI 25kg/m2 or higher, children and adolescents with BMI 85th percentile or higher
Age in the registry: 10 years to 70 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Recruiting |
| Childrens Hospital of Philadelphia Coordinator of this site? Confirm its status | Philadelphia | United States | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.