NCT04025229Completed
High Intensity Interval Training in Endometrial Cancer
Pre-operative Window Study of Interval Exercise Training as a Therapy for Endometrial Cancer
Source: ClinicalTrials.gov · Last updated 15 Oct 2025
Brief summary (registry, in English)
This interventional trial recruits women with endometrial cancer to participate in high intensity interval training (HIIT) prior to their standard of care surgery. The study will evaluate tissue and blood to determine if HIIT training has anti-cancer effects. P
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 30 (actual)
- First submitted
- 16 Jul 2019
- Start date
- 23 Sept 2019
- Primary completion date
- 8 Sept 2024
- Lead sponsor
- UNC Lineberger Comprehensive Cancer Center
- Diseases
- Endometrial cancer
- NCT number
- NCT04025229
What you commit to
- Study type: Interventional
- Participants enrolled: 30
- From 23 Sept 2019 to the primary completion date, 8 Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Hospitalization for a stroke, heart attack, or heart failure, or had surgery for blocked arteries in the past 3 months
- Active diagnosis of psychosis or current uncontrolled substance abuse disorder
- Insulin-dependent diabetes
- Severe dementia or other memory loss condition
- Severe mental health disorder
- Musculoskeletal or neuromuscular condition that limits physical activity Any condition, in the opinion of the investigators, which would prohibit safe participation.
Other
- Meets American College of Sports Medicine Guidelines for physical activity (150 minutes / week)
- Currently doing HIIT
- Currently in another EC intervention
- Severely impaired hearing or speech
- Inability to speak English
Who the study is looking for
- Patients with a diagnosis of endometrial cancer who are to undergo hysterectomy and staging
- Between 40-75 years old
- Body mass index of 30-50 kg/m2
- Endometrioid histology endometrial cancer
- Presumed clinically early stage disease (disease confined to uterus only)
- Have access to a Smart Phone
- Have access to email
- Agree to visit the exercise and sport science laboratory within 2 days of SOC visit for baseline testing if enrollment procedures cannot be done on the same day.
- Agree to visit clinic 2 (+/-2wks) weeks after surgery for SOC follow-up and post surgery visit, or willing to return to exercise and sport science laboratory 2 (+/-2wks) weeks post-surgery
Age in the registry: 18 years to 75 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UNC Lineberger Comprehensive Cancer Center Coordinator of this site? Confirm its status | Chapel Hill | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.