NCT04039672Completed
Interest of Tumor Replicates in Avian Embryo to Model Therapeutic Effects of BRAFi/MEKi in BRAF Mutated Melanoma
Interest of Tumor Replicates in Avian Embryo to Model Therapeutic Effects of BRAF Inhibitors/MEK Inhibitors (BRAFi/MEKi) in BRAF Mutated Melanoma
Source: ClinicalTrials.gov · Last updated 10 Oct 2024
Brief summary (registry, in English)
This is an interventional mono-centric study in patients with BRAF mutated metastatic melanoma treated with BRAF/MEK inhibitors. The aim of the study is to test the grafting of patient tumoral cells in avian embryo and develop a predictive in vivo model for patient treatment response.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 10 (actual)
- First submitted
- 15 May 2019
- Start date
- 2 Apr 2021
- Primary completion date
- 2 Jul 2024
- Lead sponsor
- Hospices Civils de Lyon
- Diseases
- Melanoma
- NCT number
- NCT04039672
What you commit to
- Study type: Interventional
- Participants enrolled: 10
- From 2 Apr 2021 to the primary completion date, 2 Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Medical, psychiatric, cognitive or other conditions that may compromise the patient's ability to understand the patient information, give informed consent, comply with the study protocol or complete the study
Other
- Ocular melanoma
- Pregnant or nursing (lactating) women
- Patients protected by law
Who the study is looking for
- Patients aged ≥ 18 years
- Signed written informed consent
- Patient with BRAF V600 mutated metastatic or unresectable melanoma histologically confirmed
- BRAFi/MEKi treatment indication
- Patient with skin tumor (excluded face and skinfold) available for biopsy
- Measurable disease as defined by RECIST v1.1 criteria
- Patient affiliated to or a beneficiary of a social security category
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Service de Dermatologie, Centre hospitalier Lyon Sud, HCL Coordinator of this site? Confirm its status | Pierre-Bénite | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.