NCT04047264Recruiting
Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions
Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions
Source: ClinicalTrials.gov · Last updated 18 Aug 2026
Brief summary (registry, in English)
This clinical trial evaluates the use of microdialysis catheters during surgery to collect biomarkers, and studies the feasibility of intra- and post-operative microdialysis during neurosurgery for central nervous system malignancies. A biomarker is a measurable indicator of the severity or presence of disease state. Information collected in this study may help doctors develop new strategies to better diagnose, monitor, and treat brain tumors.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 29 Jul 2019
- Start date
- 1 Jan 2020
- Primary completion date
- 1 Sept 2027
- Lead sponsor
- Mayo Clinic
- Diseases
- Glioblastoma
- NCT number
- NCT04047264
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 1 Jan 2020 to the primary completion date, 1 Sept 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who are not appropriate candidates for surgery due to current or past medical history or uncontrolled concurrent illness
Other
- Vulnerable populations: pregnant women, prisoners or the mentally handicapped
Who the study is looking for
- Age \>= 18 years
- Diagnosis of the following, based on clinical and radiographic evidence:
- Any glioma
- Metastatic brain tumor of any primary origin
- Epileptic focus requiring surgical resection
- Planned neurosurgical procedure for purposes of biopsy or resection of suspected or previously diagnosed brain tumor (primary or metastatic) or epileptic focus as part of routine clinical care
- Willing to undergo neurosurgical resection or biopsy at Mayo Clinic \[Rochester, Minnesota (MN)\]
- For patients with gliomas recruited for post-operative microdialysis, willingness to stay in the hospital through post-operative day (POD) 3-5 (timing per physician and patient's shared decision making)
- Ability to understand and the willingness to sign a written informed consent document
- Enrollment into the Biobank study (IRB#12-003458)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Clinic in Rochester Coordinator of this site? Confirm its status | Rochester | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.