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NCT04053855Recruiting

Evaluation of Urinary Exosomes Presence From Clear Cell Renal Cell Carcinoma

Source: ClinicalTrials.gov · Last updated 6 May 2026

Brief summary (registry, in English)

Clear cell renal cell carcinoma is diagnosed by imaging, sometimes associated with biopsy. This diagnosis is expensive, invasive and sometimes late. The development of a simple biological test for diagnosis is essential. Exosomes are 30 to 150 nm membrane vesicles secreted into the extracellular space by various living cells. These exosomes can be isolated from biological fluids, including urine. The recent study of urinary exosomes is a promising topic for analyzing tumor markers in urine. The investigator's goal is to develop a reliable technique for detecting tumor exosomes in urine in patients with clear cell renal cell carcinoma. The analysis of urinary exosomes could provide a new liquid biopsy tool for the early diagnosis of clear cell renal cell carcinoma.

Status (registry)
Recruiting
Study type
Observational
Enrollment
100 (estimated)
First submitted
9 Aug 2019
Start date
29 Jan 2020
Primary completion date
1 Aug 2026
Lead sponsor
Centre Hospitalier Universitaire de Saint Etienne
NCT number
NCT04053855

What you commit to

  • Study type: Observational
  • Planned participants: 100
  • From 29 Jan 2020 to the primary completion date, 1 Aug 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Insufficient volume of urine sample (\< 100 ml)
  • Patients with a urinary catheter
  • Patients under court-ordered guardianship or curators

Who the study is looking for

  • Patients:
  • All patients with renal mass requiring surgery (partial or total nephrectomy)
  • Social security affiliation
  • Signed informed consent
    • Control :
  • Unscheduled nephrectomy
  • Social security affiliation
  • Signed informed consent

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
CHU Saint-Etienne
Coordinator of this site? Confirm its status
Saint-EtienneFranceRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.