NCT04053855Recruiting
Evaluation of Urinary Exosomes Presence From Clear Cell Renal Cell Carcinoma
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
Clear cell renal cell carcinoma is diagnosed by imaging, sometimes associated with biopsy. This diagnosis is expensive, invasive and sometimes late. The development of a simple biological test for diagnosis is essential. Exosomes are 30 to 150 nm membrane vesicles secreted into the extracellular space by various living cells. These exosomes can be isolated from biological fluids, including urine. The recent study of urinary exosomes is a promising topic for analyzing tumor markers in urine. The investigator's goal is to develop a reliable technique for detecting tumor exosomes in urine in patients with clear cell renal cell carcinoma. The analysis of urinary exosomes could provide a new liquid biopsy tool for the early diagnosis of clear cell renal cell carcinoma.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 9 Aug 2019
- Start date
- 29 Jan 2020
- Primary completion date
- 1 Aug 2026
- Lead sponsor
- Centre Hospitalier Universitaire de Saint Etienne
- Diseases
- Kidney cancer
- NCT number
- NCT04053855
What you commit to
- Study type: Observational
- Planned participants: 100
- From 29 Jan 2020 to the primary completion date, 1 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Insufficient volume of urine sample (\< 100 ml)
- Patients with a urinary catheter
- Patients under court-ordered guardianship or curators
Who the study is looking for
- Patients:
- All patients with renal mass requiring surgery (partial or total nephrectomy)
- Social security affiliation
- Signed informed consent
- Control :
- Unscheduled nephrectomy
- Social security affiliation
- Signed informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU Saint-Etienne Coordinator of this site? Confirm its status | Saint-Etienne | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.