NCT04061135Recruiting
Neurophysiological, Behavioral, and Cognitive Networks in Movement Disorders
Source: ClinicalTrials.gov · Last updated 17 Mar 2026
Brief summary (registry, in English)
The purpose of this study is to investigate the brain activity associated with motor and non-motor symptoms of movement disorders, including Parkinson's disease (PD) and essential tremor. These movement disorders commonly have significant non-motor features, such as depression, cognitive and memory impairment, decreased attention, speech and language disturbances, and slower processing speeds. The investigators are interested in the brain activity associated with these motor and non-motor symptoms, and propose to investigate changes in brain activity while the investigators perform recordings of the surface and deep structures of the brain, in addition to the typical recordings the investigators perform, during routine deep brain stimulation (DBS) surgery.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 90 (estimated)
- First submitted
- 16 Jul 2019
- Start date
- 1 Sept 2019
- Primary completion date
- 31 Mar 2028
- Lead sponsor
- University of Alabama at Birmingham
- Diseases
- Parkinson disease
- NCT number
- NCT04061135
What you commit to
- Study type: Interventional
- Planned participants: 90
- From 1 Sept 2019 to the primary completion date, 31 Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Have a clinical presentation for which DBS surgery is not indicated
Other illness
- Are not surgical candidates due to co-morbid conditions or pregnancy
Other
- Inability to provide full and informed consent
- Have not undergone an adequate trial of conservative medical management
- Are not able to participate in study-related activities
Who the study is looking for
- Eligible for DBS surgery based on multi-disciplinary consensus review
- Have a diagnosis of Parkinson's disease or Essential Tremor
- A minimum of 18 years of age
- Willingness to participate in the paradigms described in the protocol
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Alabama at Birmingham Coordinator of this site? Confirm its status | Birmingham | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.