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NCT04081285Completed

Epigenetic Biomarkers for Alzheimer's Disease

Identification of Epigenetic Biomarkers for Alzheimer's Disease in Blood Using Epigenome-wide Analysis

Source: ClinicalTrials.gov · Last updated 29 Apr 2025

Brief summary (registry, in English)

Alzheimer's disease (AD) is a neurodegenerative disorder with no know cure. The pathogenesis of late onset AD (LOAD) is complex and multifactorial in nature, with multiple susceptibility genes and environmental factors at interplay. The objective of this study is to improve our understanding of the risk factors of LOAD by conducting an epigenome wide study within patients of LOAD contrasted against their cognitively normal siblings.

Status (registry)
Completed
Study type
Observational
Enrollment
250 (actual)
First submitted
23 Jul 2019
Start date
1 Sept 2019
Primary completion date
30 Nov 2024
Lead sponsor
Chinese University of Hong Kong
NCT number
NCT04081285

What you commit to

  • Study type: Observational
  • Participants enrolled: 250
  • From 1 Sept 2019 to the primary completion date, 30 Nov 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Subjects who refuse blood taking procedure
  • Do not have a reliable family/caregiver informant (personal contact at least once a month)

Who the study is looking for

  • Sufficient Cantonese competency for cognitive test
  • Written informed consent given
  • Have at least one gender-matched cognitively normal sibling

Age in the registry: 50 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
The Chinese University of Hong Kong
Coordinator of this site? Confirm its status
Hong KongHong Kong SAR ChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.